Reaction profile

The FDA adverse-event record for ocular discharge

1,937 FDA adverse-event reports reference ocular discharge (VeDDRA 468). See the species, breeds, and drugs most associated with it below.

1,937
reports citing this reaction
12.8%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
1,937
Total Reports
247
Deaths
12.8%
Death Rate

Species Most Affected

Dog 1,437
Cat 438
Cattle 26
Human 17
Horse 11
Chicken 3
Pig 3
Sheep 1
Duck 1

Breeds Most Affected

Domestic Shorthair 244
Retriever - Labrador 119
Crossbred Canine/dog 107
Shih Tzu 93
Chihuahua 69
Maltese 50
Terrier - Yorkshire 49
Retriever - Golden 41
Shepherd Dog - German 36
Boxer (German Boxer) 36

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 162
Milbemycin Oxime + Spinosad 153
Oclacitinib Maleate 129
Maropitant Citrate 124
Carprofen 103
Afoxolaner 101
Prednisone 92
Selamectin 83
Cefovecin 69
Gabapentin 68
Spinosad 63
Imidacloprid + Moxidectin 63
Moxidectin 62
Fluralaner Chew Tablets 61
Ivermectin + Pyrantel As Pamoate Salt 58
Enrofloxacin 55
Bedinvetmab 49
Lotilaner 46
Cyclosporine 44
Milbemycin Oxime + Praziquantel 44

Ocular discharge Reaction Insights

1,937 reports name Ocular discharge; 247 recorded a death outcome (12.8% of reported events, not a population-level mortality rate). VeDDRA code: 468.

By species: Dog (1,437 reports), Cat (438 reports), Cattle (26 reports). By breed: Domestic Shorthair (244), Retriever - Labrador (119), Crossbred Canine/dog (107).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (162 reports), Milbemycin Oxime + Spinosad (153 reports), Oclacitinib Maleate (129 reports), Maropitant Citrate (124 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.