Reaction profile

The FDA adverse-event record for ocular discharge

2,022 FDA reports name ocular discharge, a high-volume reaction in the CVM extract (VeDDRA 468). Plate stamps and neighbourhood peers follow.

#228 of 2,481
by report volume (all reactions)
2,022
reports citing this reaction
12.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ocular discharge has 2,022 reports now versus 1,994 in that prior snapshot: 28 more (1.4%).

Report change
+28
Death-coded reports
+2
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ocular discharge changes

FDA AER · VeDDRA plate

Code 468 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,022 reports
  • DEATH-ELEV 12.9%
  • TOP-DECILE #228/2481
  • PHOTO-FINISH Urine abnormalities N…
  • SPECIES-DOG Dog · 1,499
  • DRUG-LEAD Florfenicol + Mom… · 171
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Urine abnormalities NOS (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Ocular discharge

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Pica NOS · near2039Urine abnormalities N… · near2026Ocular discharge · this reac…2022Application site prur… · near2009INEFFECTIVE, WHIPS · near2007Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ocular discharge

What the FDA AER plate says about Ocular discharge

Signature read: 260 death-coded reports is a heavy tail count for Ocular discharge in the CVM extract. Report volume is upper-third scale: 2,022 named reports in the openFDA extract. 260 of 2,022 reports were death-coded (12.9% of named reports, not a population mortality rate). Nearest volume peer: Urine abnormalities NOS (±4 reports). Lead species Dog (1,499). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (171).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,499
Cat 460
Cattle 27
Human 17
Horse 11
Chicken 3
Pig 3
Sheep 1
Duck 1

Breeds Most Affected

Domestic Shorthair 258
Retriever - Labrador 122
Crossbred Canine/dog 110
Shih Tzu 97
Chihuahua 70
Terrier - Yorkshire 53
Maltese 52
Retriever - Golden 45
Domestic Longhair 39
Shepherd Dog - German 36

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 171
Milbemycin Oxime + Spinosad 154
Maropitant Citrate 141
Oclacitinib Maleate 133
Carprofen 111
Afoxolaner 108
Prednisone 98
Selamectin 84
Cefovecin 72
Gabapentin 72
Spinosad 63
Imidacloprid + Moxidectin 63
Moxidectin 62
Fluralaner Chew Tablets 61
Ivermectin + Pyrantel As Pamoate Salt 58
Bedinvetmab 57
Enrofloxacin 55
Lotilaner 47
Cyclosporine 46
Milbemycin Oxime + Praziquantel 45

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ocular discharge, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,022 here).

Similar death-coded share

Nearest other reactions by death-coded share (12.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ocular discharge (#228 of 2,481 by report volume); death-coded 12.9%. PlainBreed reaction plate · death-coded report count stamp 260 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →