Reaction profile

The FDA adverse-event record for epistaxis

678 FDA adverse-event reports reference epistaxis (VeDDRA 864). See the species, breeds, and drugs most associated with it below.

678
reports citing this reaction
35.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
678
Total Reports
239
Deaths
35.3%
Death Rate

Species Most Affected

Dog 554
Cat 65
Horse 27
Cattle 26
Other 1
Sheep 1
Pig 1
Human 1
Ferret 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 70
Crossbred Canine/dog 66
Shepherd Dog - German 35
Retriever - Golden 31
Domestic Shorthair 25
Dog (unknown) 17
Beagle 16
Domestic (unspecified) 15
Shepherd Dog - Australian 14
Rottweiler 12

Associated Drugs

Carprofen 97
Oclacitinib Maleate 58
Maropitant Citrate 37
Deracoxib 36
Moxidectin 29
Milbemycin Oxime + Spinosad 28
Trilostane 28
Bedinvetmab 28
Afoxolaner 25
Firocoxib 23
Enrofloxacin 22
Doxycycline 22
Prednisone 22
Melarsomine Dihydrochloride 21
Meloxicam 21
Cefovecin 19
Polysulfated Glycosaminoglycan 18
Tramadol 17
Fluralaner Chew Tablets 17
Grapiprant 16

Epistaxis Reaction Insights

678 reports name Epistaxis; 239 recorded a death outcome (35.3% of reported events, not a population-level mortality rate). VeDDRA code: 864.

By species: Dog (554 reports), Cat (65 reports), Horse (27 reports). By breed: Retriever - Labrador (70), Crossbred Canine/dog (66), Shepherd Dog - German (35).

Most co-reported drugs: Carprofen (97 reports), Oclacitinib Maleate (58 reports), Maropitant Citrate (37 reports), Deracoxib (36 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.