Acute haemorrhagic pancreatitis

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VeDDRA Code: 331

13 adverse event reports referencing this reaction

13
Total Reports
11
Deaths
8460.0%
Death Rate

Species Most Affected

Dog 9
Cat 4

Breeds Most Affected

Domestic Shorthair 4
Sheepdog (unspecified) 2
Schnauzer - Miniature 1
Retriever - Golden 1
Spitz - German Pomeranian 1
Chihuahua 1
Collie - Border 1
Dachshund - Miniature 1
Shepherd Dog - Australian 1

Associated Drugs

Spinosad 3
Milbemycin Oxime + Spinosad 2
Ampicillin Trihydrate 2
Robenacoxib 2
Buprenorphine 2
Cefazolin 2
Propofol 2
Isoflurane 2
Firocoxib 227 Mg Chewable 1
Vaccines (Unknown) 1
Meloxicam 1
Fluralaner Chew Tablets 1
Cefovecin Sodium 1
Oclacitinib Maleate 1
Da2Ppl Vaccine 1
Rabies Vaccine 1
Bordetella Vaccine 1
Phenylpropropanolamine Hcl 1
Cetirizine 1
Vitamin B12 1

Data Summary

Metric Value
Total reports referencing reaction 13
Reports with fatal outcome 11
Case-fatality rate (reported events) 8460.0%
Species observed 2
Breeds observed 9
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 331.

Acute haemorrhagic pancreatitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 13 adverse event reports that reference Acute haemorrhagic pancreatitis as a reaction term, including 11 reports with a death outcome — a 8460.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 331, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Acute haemorrhagic pancreatitis appears most frequently in reports for Dog (9 reports), Cat (4 reports) — with Dog dominating at 9 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (4), Sheepdog (unspecified) (2), Schnauzer - Miniature (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Acute haemorrhagic pancreatitis are Spinosad (3 reports), Milbemycin Oxime + Spinosad (2 reports), Ampicillin Trihydrate (2 reports), Robenacoxib (2 reports), with Spinosad appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial