Reaction profile

The FDA adverse-event record for face and neck swelling (see also 'skin')

244 FDA adverse-event reports reference face and neck swelling (see also 'skin') (VeDDRA 1462). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#948 of 2,481
by report volume (all reactions)
244
reports citing this reaction
9.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Face and neck swelling (see also 'Skin') has 202 reports now versus 202 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Face and neck swelling (see also 'Skin') changes

FDA AER · VeDDRA plate

Code 1462 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 244 reports
  • DEATH-PAR 9.4%
  • MID-PACK #948/2481
  • PHOTO-FINISH Abnormal posture
  • SPECIES-DOG Dog · 169
  • DRUG-LEAD Moxidectin · 46
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal posture (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Face and neck swelling

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Small liver · near245Abnormal posture · near244Face and neck swellin… · thi…244HEMATOCRIT(HCT) HIGH,… · near244Acidosis · near242Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Face and neck swelling (see also 'Skin')

What the FDA AER plate says about Face and neck swelling (see also 'Skin')

Signature read: death-coded share at 9.4% is the most distinctive outcome stamp on Face and neck swelling (see also 'Skin'). Report volume sits in the middle third of the reaction corpus. 23 of 244 reports were death-coded (9.4% of named reports, not a population mortality rate). Nearest volume peer: Abnormal posture (±0 reports). Lead species Dog (169). Lead co-reported drug Moxidectin (46).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 169
Horse 15
Cattle 7
Cat 6
Human 4
Bat 1

Breeds Most Affected

Chihuahua 19
Retriever - Labrador 17
Boxer (German Boxer) 13
Crossbred Canine/dog 10
Terrier - Bull - American Pit 9
Unknown 7
Retriever - Golden 6
Pit Bull 6
Terrier - Jack Russell 6
Dog (unknown) 5

Associated Drugs

Moxidectin 46
Milbemycin Oxime + Spinosad 24
Afoxolaner 12
Rabies Virus, 11
Fluralaner Chew Tablets 8
Oclacitinib Maleate 8
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 8
Ivermectin + Pyrantel As Pamoate Salt 7
Maropitant Citrate 7
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 7
Prednisone 6
Diphenhydramine Hcl 5
Cefovecin 4
Isoflurane 4
Ceftiofur Crystalline Free Acid 4
Firocoxib 4
Anti-Il31 Mab Mcs Lot #1283563 4
Fluralaner 13.64% 12-Week Chew 4
Pyrantel Pamoate;Sarolaner 4
Carprofen 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Face and neck swelling (see also 'Skin'), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (244 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Face and neck swelling (see also 'Skin') (#948 of 2,481 by report volume); death-coded 9.4%. PlainBreed reaction plate · death-coded share stamp 9.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →