Reaction profile

The FDA adverse-event record for bladder incontinence

293 FDA adverse-event reports reference bladder incontinence (VeDDRA 1346). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#875 of 2,481
by report volume (all reactions)
293
reports citing this reaction
22.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bladder incontinence has 293 reports now versus 292 in that prior snapshot: 1 more (0.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bladder incontinence changes

FDA AER · VeDDRA plate

Code 1346 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 293 reports
  • DEATH-HOT 22.5%
  • MID-PACK #875/2481
  • PHOTO-FINISH Anaphylactic shock
  • SPECIES-DOG Dog · 265
  • DRUG-LEAD Milbemycin Oxime… · 55
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anaphylactic shock (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Bladder incontinence

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abortion · near294Exercise intolerance · near294Anaphylactic shock · near293Bladder incontinence · this …293Vaginal discharge · near293Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Bladder incontinence

What the FDA AER plate says about Bladder incontinence

Signature read: 66 death-coded reports is a heavy tail count for Bladder incontinence in the CVM extract. Report volume sits in the middle third of the reaction corpus. 66 of 293 reports were death-coded (22.5% of named reports, not a population mortality rate). Nearest volume peer: Anaphylactic shock (±0 reports). Lead species Dog (265). Lead co-reported drug Milbemycin Oxime + Spinosad (55).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 265
Cat 28

Breeds Most Affected

Retriever - Labrador 28
Crossbred Canine/dog 20
Boxer (German Boxer) 16
Domestic Shorthair 15
Retriever - Golden 14
Dog (unknown) 11
Shepherd Dog - German 10
Terrier - Yorkshire 8
Shepherd Dog - Australian 8
Maltese 7

Associated Drugs

Milbemycin Oxime + Spinosad 55
Afoxolaner 34
Bedinvetmab 31
Carprofen 23
Ivermectin + Pyrantel As Pamoate Salt 16
Milbemycin Oxime + Praziquantel 16
Gabapentin 15
Sarolaner 13
Fluralaner Chew Tablets 13
Pyrantel Pamoate;Sarolaner 13
Fluralaner 13.64% 12-Week Chew 11
Lotilaner 11
Selamectin 9
Oclacitinib Maleate 9
Moxidectin 9
Spinosad 8
Pimobendan 7
Buprenorphine 7
Ivermectin 6
Cefovecin 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Bladder incontinence, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (293 here).

Similar death-coded share

Nearest other reactions by death-coded share (22.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bladder incontinence (#875 of 2,481 by report volume); death-coded 22.5%. PlainBreed reaction plate · death-coded report count stamp 66 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →