Reaction profile

The FDA adverse-event record for anisocytosis

47 FDA reports name anisocytosis, a lower-volume reaction in the CVM extract (VeDDRA 99332). Plate stamps and neighbourhood peers follow.

#1768 of 2,481
by report volume (all reactions)
47
reports citing this reaction
23.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. ANISOCYTOSIS has 47 reports now versus 47 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to ANISOCYTOSIS changes

FDA AER · VeDDRA plate

Code 99332 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 47 reports
  • DEATH-HOT 23.4%
  • MID-PACK #1768/2481
  • PHOTO-FINISH Abnormal number of of…
  • SPECIES-DOG Dog · 38
  • DRUG-LEAD Carprofen · 5
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal number of offspring (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around ANISOCYTOSIS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal number of of… · near47ALBUMIN/GLOBULIN RATI… · near47ANISOCYTOSIS · this reaction47Blood in trachea · near47Exocrine pancreatic i… · near47Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around ANISOCYTOSIS

What the FDA AER plate says about ANISOCYTOSIS

Signature read: 47 reports place ANISOCYTOSIS in the lower third of FDA AER volume (#1768 of 2,481). Report volume is lower-third scale: 47 named reports in the openFDA extract. 11 of 47 reports were death-coded (23.4% of named reports, not a population mortality rate). Nearest volume peer: Abnormal number of offspring (±0 reports). Lead species Dog (38). Lead co-reported drug Carprofen (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 38
Cat 9

Breeds Most Affected

Crossbred Canine/dog 4
Retriever - Labrador 4
Domestic (unspecified) 3
Schnauzer (unspecified) 3
Retriever - Golden 3
Domestic Shorthair 3
Terrier - Yorkshire 2
Greyhound - Italian 2
Lhasa Apso 2
Shepherd Dog - German 2

Associated Drugs

Carprofen 5
Milbemycin Oxime + Spinosad 5
Spinosad 4
Cefovecin Sodium 4
Cefovecin 4
Ivermectin + Pyrantel As Pamoate Salt 4
Meloxicam 3
Cyclosporine 3
Selamectin 3
Afoxolaner 3
Firocoxib 2
Moxidectin 2
Prednisone 2
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 2
Morphine 2
Deracoxib 2
Fluralaner Chew Tablets 2
Marbofloxacin 1
Acepromazine Maleate 1
Cefpodoxime Proxetil 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for ANISOCYTOSIS (#1768 of 2,481 by report volume); death-coded 23.4%. PlainBreed reaction plate · report volume stamp 47 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →