Reaction profile

The FDA adverse-event record for chapped skin

Name: Chapped skin - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

14 FDA reports name chapped skin, a lower-volume reaction in the CVM extract (VeDDRA 1374). Plate stamps and neighbourhood peers follow.

#2321 of 2,481
by report volume (all reactions): 14
reports citing this reaction: 14.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chapped skin has 14 reports now versus 12 in that prior snapshot: 2 more (16.7%).

Report change: +2
Death-coded reports: +0
Death-coded share: −2.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chapped skin changes

FDA AER · VeDDRA plate

Code 1374 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 14 reports
DEATH-ELEV 14.3%
BOTTOM-DECILE #2321/2481
PHOTO-FINISH Addisonian crisis
SPECIES-DOG Dog · 9
DRUG-LEAD Cyclosporine · 5
DESK-WIDE 11 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Addisonian crisis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Chapped skin

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Chapped skin

What the FDA AER plate says about Chapped skin

Signature read: 14 reports place Chapped skin in the lower third of FDA AER volume (#2321 of 2,481). Report volume is lower-third scale: 14 named reports in the openFDA extract. 2 of 14 reports were death-coded (14.3% of named reports, not a population mortality rate). Nearest volume peer: Addisonian crisis (±0 reports). Lead species Dog (9). Lead co-reported drug Cyclosporine (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Cyclosporine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 9

Human 3

Cat 2

Breeds Most Affected

Unknown 3

Bulldog - English 2

Plott 1

Terrier - West Highland White 1

Akita 1

Crossbred Canine/dog 1

Rottweiler 1

Cat (unknown) 1

Domestic Shorthair 1

Shepherd Dog - Australian 1

Associated Drugs

Cyclosporine 5

Selamectin 2

Oclacitinib Maleate 2

Carprofen 2

Prednisone 2

Trilostane 2

Milbemycin Oxime + Spinosad 1

Topical Spray 1

Tilmicosin Phosphate 1

Fluralaner Chew Tablets 1

Nitenpyram 1

Deracoxib 1

Amoxicillin Trihydrate, Potassium Clavulanate 1

Cefovecin 1

Oclacitinib Tablet 1

Pyrantel Pamoate;Sarolaner 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chapped skin (#2321 of 2,481 by report volume); death-coded 14.3%. PlainBreed reaction plate · report volume stamp 14 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →