Reaction profile

The FDA adverse-event record for eye pain

341 FDA adverse-event reports reference eye pain (VeDDRA 1458). See the species, breeds, and drugs most associated with it below.

341
reports citing this reaction
2.9%
death-coded share
Human
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
341
Total Reports
10
Deaths
2.9%
Death Rate

Species Most Affected

Human 157
Dog 151
Cat 27
Horse 3
Goat 2
Cattle 1

Breeds Most Affected

Unknown 160
Chihuahua 19
Shih Tzu 18
Domestic Shorthair 13
Crossbred Canine/dog 8
Dachshund (unspecified) 7
Domestic Longhair 7
Retriever - Labrador 7
Boxer (German Boxer) 6
Pinscher - Miniature 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 42
Imidacloprid + Moxidectin 23
Meloxicam 17
Carprofen 17
Selamectin 15
Maropitant Citrate 14
Prednisone 14
Hyaluronic Acid 13
Oclacitinib Maleate 12
Dexamethasone, Neomycin, Thiabendazole 10
Tresaderm Dermatological Solution 10
Milbemycin Oxime + Spinosad 10
Florfenicol, Terbinafine, Betamethasone Acetate 10
Artificial Tears 9
Ivermectin 8
Moxidectin 8
Ofloxacin 8
Tobramycin 8
Dexamethasone + Neomycin Sulfate + Thiabendazole 7
Enrofloxacin 6

Eye pain Reaction Insights

341 reports name Eye pain; 10 recorded a death outcome (2.9% of reported events, not a population-level mortality rate). VeDDRA code: 1458.

By species: Human (157 reports), Dog (151 reports), Cat (27 reports). By breed: Unknown (160), Chihuahua (19), Shih Tzu (18).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (42 reports), Imidacloprid + Moxidectin (23 reports), Meloxicam (17 reports), Carprofen (17 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.