Monoparesis (paralysis of limb)

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VeDDRA Code: 1617

57 adverse event reports referencing this reaction

57
Total Reports
18
Deaths
3160.0%
Death Rate

Species Most Affected

Dog 42
Cat 9
Other Birds 3
Pig 1
Cattle 1
Horse 1

Breeds Most Affected

Domestic Shorthair 6
Retriever - Labrador 3
Terrier - Bull - American Pit 3
Schnauzer - Miniature 2
Terrier - Yorkshire 2
Boxer (German Boxer) 2
Cat (unknown) 2
Crossbred Canine/dog 2
Beagle 2
Chihuahua 2

Associated Drugs

Bedinvetmab 14
Gabapentin 10
Milbemycin Oxime + Spinosad 6
Afoxolaner 4
Carprofen 4
Prednisone 3
Ivermectin + Pyrantel As Pamoate Salt 3
Grapiprant 3
Metronidazole 2
Spinosad 2
Robenacoxib 2
Enrofloxacin 2
Sevoflurane 2
Doxycycline 2
Polysulfated Glycosaminoglycan 2
Imidacloprid + Moxidectin 2
Fluralaner 13.64% 12-Week Chew 2
Thyroid Medication 2
Robenocoxib 2
Insulin 2

Data Summary

Metric Value
Total reports referencing reaction 57
Reports with fatal outcome 18
Case-fatality rate (reported events) 3160.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1617.

Monoparesis (paralysis of limb) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 57 adverse event reports that reference Monoparesis (paralysis of limb) as a reaction term, including 18 reports with a death outcome — a 3160.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1617, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Monoparesis (paralysis of limb) appears most frequently in reports for Dog (42 reports), Cat (9 reports), Other Birds (3 reports) — with Dog dominating at 42 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (6), Retriever - Labrador (3), Terrier - Bull - American Pit (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Monoparesis (paralysis of limb) are Bedinvetmab (14 reports), Gabapentin (10 reports), Milbemycin Oxime + Spinosad (6 reports), Afoxolaner (4 reports), with Bedinvetmab appearing alongside this reaction in 14 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial