Reaction profile

The FDA adverse-event record for haemorrhagic diarrhoea

661 FDA reports name haemorrhagic diarrhoea, a high-volume reaction in the CVM extract (VeDDRA 314). Plate stamps and neighbourhood peers follow.

#536 of 2,481
by report volume (all reactions)
661
reports citing this reaction
17.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Haemorrhagic diarrhoea has 661 reports now versus 653 in that prior snapshot: 8 more (1.2%).

Report change
+8
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Haemorrhagic diarrhoea changes

FDA AER · VeDDRA plate

Code 314 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 661 reports
  • DEATH-ELEV 17.5%
  • UPPER-Q #536/2481
  • PHOTO-FINISH Difficulty to rise
  • SPECIES-DOG Dog · 632
  • DRUG-LEAD Moxidectin · 74
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Difficulty to rise (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Haemorrhagic diarrhoea

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Urine leakage · near668Disoriented state · near666Difficulty to rise · near665Haemorrhagic diarrhoea · thi…661Low thyroxine (T4) · near653Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Haemorrhagic diarrhoea

What the FDA AER plate says about Haemorrhagic diarrhoea

Signature read: 116 death-coded reports is a heavy tail count for Haemorrhagic diarrhoea in the CVM extract. Report volume is upper-third scale: 661 named reports in the openFDA extract. 116 of 661 reports were death-coded (17.5% of named reports, not a population mortality rate). Nearest volume peer: Difficulty to rise (±4 reports). Lead species Dog (632). Lead co-reported drug Moxidectin (74).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 632
Cat 25
Cattle 4

Breeds Most Affected

Retriever - Labrador 63
Crossbred Canine/dog 36
Terrier - Yorkshire 29
Shepherd Dog - German 27
Terrier - Bull - American Pit 23
Chihuahua 20
Boxer (German Boxer) 20
Retriever - Golden 19
Dog (unknown) 18
Shih Tzu 18

Associated Drugs

Moxidectin 74
Carprofen 71
Maropitant Citrate 47
Ivermectin + Pyrantel As Pamoate Salt 46
Trilostane 40
Afoxolaner 40
Imidacloprid + Moxidectin 33
Milbemycin Oxime + Spinosad 33
Metronidazole 31
Isoflurane 30
Meloxicam 29
Melarsomine Dihydrochloride 28
Oclacitinib Maleate 25
Gabapentin 21
Diphenhydramine Hcl 20
Propofol 18
Grapiprant 18
Pyrantel Pamoate;Sarolaner 17
Febantel + Praziquantel + Pyrantel Pamoate 15
Melarsomine Dihydrochloride Injection 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Haemorrhagic diarrhoea, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (661 here).

Similar death-coded share

Nearest other reactions by death-coded share (17.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Haemorrhagic diarrhoea (#536 of 2,481 by report volume); death-coded 17.5%. PlainBreed reaction plate · death-coded report count stamp 116 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →