Reaction profile

The FDA adverse-event record for demodicosis

230 FDA adverse-event reports reference demodicosis (VeDDRA 2587). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#972 of 2,481
by report volume (all reactions)
230
reports citing this reaction
2.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Demodicosis has 230 reports now versus 229 in that prior snapshot: 1 more (0.4%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Demodicosis changes

FDA AER · VeDDRA plate

Code 2587 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 230 reports
  • DEATH-LOW 2.2%
  • MID-PACK #972/2481
  • PHOTO-FINISH Elevated thyroxine (T…
  • SPECIES-DOG Dog · 227
  • DRUG-LEAD Oclacitinib Malea… · 131
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated thyroxine (T4) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Demodicosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Demodicosis · this reaction230Elevated thyroxine (T… · near230Partial blindness · near228Poor coat condition · near228Application site self… · near227Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Demodicosis

Demodicosis: low death-coded share in the FDA AER plate

Signature read: Demodicosis's 2.2% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 5 of 230 reports (2.2% of named reports). Nearest volume peer: Elevated thyroxine (T4) (±0 reports). Lead species Dog (227). Lead co-reported drug Oclacitinib Maleate (131).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 227
Cat 3

Breeds Most Affected

Dog (unknown) 28
Retriever - Labrador 22
Shih Tzu 16
Bulldog 12
Pit Bull 11
Terrier - Bull - American Pit 11
Shepherd Dog - German 10
Crossbred Canine/dog 9
Terrier - Yorkshire 8
Chihuahua 8

Associated Drugs

Oclacitinib Maleate 131
Milbemycin Oxime + Spinosad 75
Anti-Il31 Mab Mcs Lot #1283563 21
Lotilaner 12
Ivermectin 9
Milbemycin Oxime + Praziquantel 9
Cephalexin 8
Fluralaner 7
Cefovecin 7
Trilostane 7
Afoxolaner 6
Prednisolone; Trimeprazine Tartrate 6
Diphenhydramine Hcl 5
Selamectin 5
Immunotherapy 4
Milbemycin Oxime 4
Antibiotic 4
Spinosad 4
Prednisone 4
Cefpodoxime Proxetil 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Demodicosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (230 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Demodicosis (#972 of 2,481 by report volume); death-coded 2.2%. PlainBreed reaction plate · death-coded share stamp 2.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →