Reaction profile

The FDA adverse-event record for cyanotic mucous membranes

111 FDA adverse-event reports reference cyanotic mucous membranes (VeDDRA 2988). See the species, breeds, and drugs most associated with it below.

111
reports citing this reaction
45.0%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
111
Total Reports
50
Deaths
45.0%
Death Rate

Species Most Affected

Dog 94
Cat 13
Horse 4

Breeds Most Affected

Domestic Shorthair 9
Retriever - Labrador 8
Bulldog - French 7
Terrier - Yorkshire 5
Chihuahua 5
Crossbred Canine/dog 5
Terrier - Bull - American Pit 4
Beagle 4
Shih Tzu 4
Terrier (unspecified) 4

Associated Drugs

Bedinvetmab 22
Moxidectin 19
Maropitant Citrate 18
Butorphanol 11
Diphenhydramine 10
Doxycycline 10
Carprofen 10
Isoflurane 9
Gabapentin 8
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 8
Rabies Vaccine 8
Furosemide 7
Propofol 7
Buprenorphine 7
Dexmedetomidine 7
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 6
Oclacitinib Maleate 6
Melarsomine Dihydrochloride 5
Rabies Virus, Kv 5
Dexamethasone 5

Cyanotic mucous membranes Reaction Insights

111 reports name Cyanotic mucous membranes; 50 recorded a death outcome (45.0% of reported events, not a population-level mortality rate). VeDDRA code: 2988.

By species: Dog (94 reports), Cat (13 reports), Horse (4 reports). By breed: Domestic Shorthair (9), Retriever - Labrador (8), Bulldog - French (7).

Most co-reported drugs: Bedinvetmab (22 reports), Moxidectin (19 reports), Maropitant Citrate (18 reports), Butorphanol (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.