Reaction profile

The FDA adverse-event record for head twitching

72 FDA adverse-event reports reference head twitching (VeDDRA 3110). See the species, breeds, and drugs most associated with it below.

72
reports citing this reaction
12.5%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
72
Total Reports
9
Deaths
12.5%
Death Rate

Species Most Affected

Dog 52
Cat 20

Breeds Most Affected

Domestic Shorthair 15
Dachshund (unspecified) 5
Crossbred Canine/dog 5
Retriever - Golden 4
Retriever - Labrador 4
Shepherd Dog - Australian 3
Terrier - Yorkshire 3
Bulldog - French 3
Dog (unknown) 3
Shepherd Dog - German 3

Associated Drugs

Bedinvetmab 20
Pyrantel Pamoate;Sarolaner 8
Gabapentin 8
Frunevetmab 7
Carprofen 7
Afoxolaner 6
Buprenorphine 5
Sarolaner 4
Selamectin;Sarolaner 4
Fluralaner 13.64% 12-Week Chew 4
Grapiprant 4
Cefovecin 3
Prednisone 3
Pimobendan 3
Phenobarbital 3
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 2
Midazolam 2
Ivermectin + Pyrantel As Pamoate Salt 2
Furosemide 2
Tigilanol Tiglate 2

Head twitching Reaction Insights

72 reports name Head twitching; 9 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). VeDDRA code: 3110.

By species: Dog (52 reports), Cat (20 reports). By breed: Domestic Shorthair (15), Dachshund (unspecified) (5), Crossbred Canine/dog (5).

Most co-reported drugs: Bedinvetmab (20 reports), Pyrantel Pamoate;Sarolaner (8 reports), Gabapentin (8 reports), Frunevetmab (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.