Reaction profile

The FDA adverse-event record for retained placenta

24 FDA adverse-event reports reference retained placenta (VeDDRA 788). See the species, breeds, and drugs most associated with it below.

24
reports citing this reaction
16.7%
death-coded share
Cattle
most-affected species
Pegbovigrastim
most-associated drug
Verify with FDA CVM →
24
Total Reports
4
Deaths
16.7%
Death Rate

Species Most Affected

Cattle 20
Dog 3
Sheep 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 13
Cattle (unknown) 2
Cattle (other) 2
Terrier - Tibetan 1
Pit Bull 1
Landseer (Continental-European type) 1
Crossbred Bovine/Cattle 1
Mixed (Cattle) 1
Aberdeen Angus 1
Sheep (other) 1

Associated Drugs

Pegbovigrastim 9
Monensin Sodium 7
Spinosad 2
Monensin 1
Thiabendazole/Neomycin/Dexamethason 1
Ivermectin 1
Cloprostenol Sodium 1
Nitenpyram 1
Clorsulon + Ivermectin 1
Doramectin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Tocopherol & Vitamins Ad 1
Moraxella Bovis Bacterin 1
Oxytetracycline Dihydrate 1
Moxidectin 1

Retained placenta Reaction Insights

24 reports name Retained placenta; 4 recorded a death outcome (16.7% of reported events, not a population-level mortality rate). VeDDRA code: 788.

By species: Cattle (20 reports), Dog (3 reports), Sheep (1 reports). By breed: Holstein-Friesian also known as Holstein (13), Cattle (unknown) (2), Cattle (other) (2).

Most co-reported drugs: Pegbovigrastim (9 reports), Monensin Sodium (7 reports), Spinosad (2 reports), Monensin (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.