Retained placenta

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VeDDRA Code: 788

24 adverse event reports referencing this reaction

24
Total Reports
4
Deaths
1670.0%
Death Rate

Species Most Affected

Cattle 20
Dog 3
Sheep 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 13
Cattle (unknown) 2
Cattle (other) 2
Terrier - Tibetan 1
Pit Bull 1
Landseer (Continental-European type) 1
Crossbred Bovine/Cattle 1
Mixed (Cattle) 1
Aberdeen Angus 1
Sheep (other) 1

Associated Drugs

Pegbovigrastim 9
Monensin Sodium 7
Spinosad 2
Monensin 1
Thiabendazole/Neomycin/Dexamethason 1
Ivermectin 1
Cloprostenol Sodium 1
Nitenpyram 1
Clorsulon + Ivermectin 1
Doramectin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 1
Tocopherol & Vitamins Ad 1
Moraxella Bovis Bacterin 1
Oxytetracycline Dihydrate 1
Moxidectin 1

Data Summary

Metric Value
Total reports referencing reaction 24
Reports with fatal outcome 4
Case-fatality rate (reported events) 1670.0%
Species observed 3
Breeds observed 10
Drugs associated with reaction 15

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 788.

Retained placenta Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 24 adverse event reports that reference Retained placenta as a reaction term, including 4 reports with a death outcome — a 1670.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 788, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Retained placenta appears most frequently in reports for Cattle (20 reports), Dog (3 reports), Sheep (1 reports) — with Cattle dominating at 20 entries. Within those species, the breeds most often named alongside this reaction are Holstein-Friesian also known as Holstein (13), Cattle (unknown) (2), Cattle (other) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Retained placenta are Pegbovigrastim (9 reports), Monensin Sodium (7 reports), Spinosad (2 reports), Monensin (1 reports), with Pegbovigrastim appearing alongside this reaction in 9 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial