Wrong technique in drug usage process

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VeDDRA Code: 99865

371 adverse event reports referencing this reaction

371
Total Reports
20
Deaths
540.0%
Death Rate

Species Most Affected

Dog 207
Cat 64
Unknown 52
Human 47
Cattle 1

Breeds Most Affected

Unknown 99
Domestic Shorthair 43
Crossbred Canine/dog 36
Retriever - Labrador 16
Schnauzer - Miniature 15
Chihuahua 11
Terrier - Yorkshire 10
Bichon Frise 9
Dog (unknown) 9
Maltese 8

Associated Drugs

Insulin Injectable Vial 218
Fluralaner Spot-On Solution 44
Cyclosporine 41
Emodepside + Praziquantel 12
Selamectin 10
Spinosad 9
Protamine Zinc Recombinant Human Insulin 6
Milbemycin Oxime + Spinosad 5
Insulin Injectable Cartridge 4
Thiamazole 2
Butorphanol Tartrate 2
Levothyroxine Sodium 2
Trilostane 2
Pentobarbital Sodium + Phenytoin Sodium 2
Desoxycortone Pivalate 2
Polysulfated Glycosaminoglycan 2
Bedinvetmab 2
Moxidectin 1
Methocarbamol 1
Carprofen 1

Data Summary

Metric Value
Total reports referencing reaction 371
Reports with fatal outcome 20
Case-fatality rate (reported events) 540.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99865.

Wrong technique in drug usage process Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 371 adverse event reports that reference Wrong technique in drug usage process as a reaction term, including 20 reports with a death outcome — a 540.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99865, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Wrong technique in drug usage process appears most frequently in reports for Dog (207 reports), Cat (64 reports), Unknown (52 reports) — with Dog dominating at 207 entries. Within those species, the breeds most often named alongside this reaction are Unknown (99), Domestic Shorthair (43), Crossbred Canine/dog (36). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Wrong technique in drug usage process are Insulin Injectable Vial (218 reports), Fluralaner Spot-On Solution (44 reports), Cyclosporine (41 reports), Emodepside + Praziquantel (12 reports), with Insulin Injectable Vial appearing alongside this reaction in 218 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial