Reaction profile

The FDA adverse-event record for wrong technique in drug usage process

371 FDA adverse-event reports reference wrong technique in drug usage process (VeDDRA 99865). See the species, breeds, and drugs most associated with it below.

371
reports citing this reaction
5.4%
death-coded share
Dog
most-affected species
Insulin Injectable Vial
most-associated drug
Verify with FDA CVM →
371
Total Reports
20
Deaths
5.4%
Death Rate

Species Most Affected

Dog 207
Cat 64
Unknown 52
Human 47
Cattle 1

Breeds Most Affected

Unknown 99
Domestic Shorthair 43
Crossbred Canine/dog 36
Retriever - Labrador 16
Schnauzer - Miniature 15
Chihuahua 11
Terrier - Yorkshire 10
Bichon Frise 9
Dog (unknown) 9
Maltese 8

Associated Drugs

Insulin Injectable Vial 218
Fluralaner Spot-On Solution 44
Cyclosporine 41
Emodepside + Praziquantel 12
Selamectin 10
Spinosad 9
Protamine Zinc Recombinant Human Insulin 6
Milbemycin Oxime + Spinosad 5
Insulin Injectable Cartridge 4
Thiamazole 2
Butorphanol Tartrate 2
Levothyroxine Sodium 2
Trilostane 2
Pentobarbital Sodium + Phenytoin Sodium 2
Desoxycortone Pivalate 2
Polysulfated Glycosaminoglycan 2
Bedinvetmab 2
Moxidectin 1
Methocarbamol 1
Carprofen 1

Wrong technique in drug usage process Reaction Insights

371 reports name Wrong technique in drug usage process; 20 recorded a death outcome (5.4% of reported events, not a population-level mortality rate). VeDDRA code: 99865.

By species: Dog (207 reports), Cat (64 reports), Unknown (52 reports). By breed: Unknown (99), Domestic Shorthair (43), Crossbred Canine/dog (36).

Most co-reported drugs: Insulin Injectable Vial (218 reports), Fluralaner Spot-On Solution (44 reports), Cyclosporine (41 reports), Emodepside + Praziquantel (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.