Reaction profile

The FDA adverse-event record for lacrimal disorder nos

26 FDA adverse-event reports reference lacrimal disorder nos (VeDDRA 441). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
19.2%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
26
Total Reports
5
Deaths
19.2%
Death Rate

Species Most Affected

Dog 21
Cat 4
Human 1

Breeds Most Affected

Retriever - Labrador 5
Domestic Shorthair 2
Bichon Frise 2
Domestic (unspecified) 1
Akita 1
Shiba Inu 1
Beagle 1
Cat (unknown) 1
Terrier - Irish 1
Boxer (German Boxer) 1

Associated Drugs

Carprofen 3
Maropitant 2
Imidacloprid + Moxidectin 2
Amoxicillin As Trihydrate; Clavulanate Potassium ( K-Clavulanate) 2
Maropitant Citrate 2
Metaclopramide 2
Trilostane 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Selamectin 1
Butorphanol Tartrate 1
Deracoxib 1
Marbofloxacin 1
Cefovecin Sodium 1
Firocoxib 1
Milbemycin Oxime + Spinosad 1
Polysulfated Glycosaminoglycan 1
Cefovecin 1
Oclacitinib Maleate 1
Febantel + Praziquantel + Pyrantel Pamoate 1
Flumethrin-Imidacloprid 1

Lacrimal disorder NOS Reaction Insights

26 reports name Lacrimal disorder NOS; 5 recorded a death outcome (19.2% of reported events, not a population-level mortality rate). VeDDRA code: 441.

By species: Dog (21 reports), Cat (4 reports), Human (1 reports). By breed: Retriever - Labrador (5), Domestic Shorthair (2), Bichon Frise (2).

Most co-reported drugs: Carprofen (3 reports), Maropitant (2 reports), Imidacloprid + Moxidectin (2 reports), Amoxicillin As Trihydrate; Clavulanate Potassium ( K-Clavulanate) (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.