Reaction profile

The FDA adverse-event record for premature anaesthesia recovery

61 FDA adverse-event reports reference premature anaesthesia recovery (VeDDRA 2278). See the species, breeds, and drugs most associated with it below.

61
reports citing this reaction
4.9%
death-coded share
Dog
most-affected species
Isoflurane
most-associated drug
Verify with FDA CVM →
61
Total Reports
3
Deaths
4.9%
Death Rate

Species Most Affected

Dog 37
Cat 14
Horse 8
Rat 1
Chinchilla 1

Breeds Most Affected

Dog (unknown) 12
Cat (unknown) 7
Unknown 6
Quarter Horse 3
Shepherd Dog - German 2
Retriever - Golden 2
Domestic Shorthair 2
Mixed (Horse) 1
Horse (unknown) 1
Spaniel - Springer (unspecified) 1

Associated Drugs

Isoflurane 23
Propofol 16
Dexmedetomidine Hydrochloride 11
Ketamine Hydrochloride 8
Dexmedetomidine 8
Buprenorphine 8
Butorphanol Tartrate 6
Ketamine 5
Butorphanol 4
Carprofen 4
Acepromazine 4
Sevoflurane 3
Dexmedetomidine Hcl 3
Atipamezole Hydrochloride 3
Alfaxalone 3
Tiletamine Hcl, Zolazepam Hcl 3
Hydromorphone 3
Xylazine 2
Buprenorphine Hcl 2
Hydromorphone Hcl Injectable 2

Premature anaesthesia recovery Reaction Insights

61 reports name Premature anaesthesia recovery; 3 recorded a death outcome (4.9% of reported events, not a population-level mortality rate). VeDDRA code: 2278.

By species: Dog (37 reports), Cat (14 reports), Horse (8 reports). By breed: Dog (unknown) (12), Cat (unknown) (7), Unknown (6).

Most co-reported drugs: Isoflurane (23 reports), Propofol (16 reports), Dexmedetomidine Hydrochloride (11 reports), Ketamine Hydrochloride (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.