Reaction profile

The FDA adverse-event record for symptom nos involving neurological and muscular skeletal socs

97 FDA adverse-event reports reference symptom nos involving neurological and muscular skeletal socs (VeDDRA 1822). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1411 of 2,481
by report volume (all reactions)
97
reports citing this reaction
34.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Symptom NOS involving neurological and muscular skeletal SOCs has 97 reports now versus 96 in that prior snapshot: 1 more (1.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Symptom NOS involving neurological and muscular skeletal SOCs changes

FDA AER · VeDDRA plate

Code 1822 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 97 reports
  • DEATH-HOT 34.0%
  • MID-PACK #1411/2481
  • PHOTO-FINISH Digestive tract steno…
  • SPECIES-DOG Dog · 68
  • DRUG-LEAD Monensin Sodium · 11
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Digestive tract stenosis and obstruction NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Symptom NOS involving neurological and muscula…

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Digestive tract steno… · near97Dysuria · near97Feeling anxious · near97Lockjaw · near97Symptom NOS involving… · thi…97Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Symptom NOS involving neurological and muscular skeletal SOCs

Symptom NOS involving neurological and muscular skeletal SOCs: high death-coded share in the FDA AER plate

Signature read: Symptom NOS involving neurological and muscular skeletal SOCs's 34.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 33 of 97 reports (34.0% of named reports). Nearest volume peer: Digestive tract stenosis and obstruction NOS (±0 reports). Lead species Dog (68). Lead co-reported drug Monensin Sodium (11).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 68
Cat 13
Turkey 10
Chicken 2
Horse 2
Cattle 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 10
Turkey (unknown) 9
Retriever - Labrador 5
Crossbred Canine/dog 4
Boxer (German Boxer) 4
Terrier - Yorkshire 4
Corgi - Welsh Pembroke 3
Dachshund (unspecified) 3
Poodle - Toy 3
Terrier - Bull - American Pit 3

Associated Drugs

Monensin Sodium 11
Sarolaner 11
Pyrantel Pamoate;Sarolaner 10
Bedinvetmab 9
Moxidectin 8
Milbemycin Oxime + Spinosad 7
Gabapentin 7
Supplement 5
Trilostane 5
Selamectin 3
Carprofen 3
Rabies Vaccine 3
Frunevetmab 3
Vaccines (Unknown) 2
Diphenhydramine 2
Buprenorphine 2
Tramadol 2
Milbemycin Oxime 2
Ivermectin + Pyrantel As Pamoate Salt 2
Oclacitinib Maleate 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Symptom NOS involving neurological and muscular skeletal SOCs, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (97 here).

Similar death-coded share

Nearest other reactions by death-coded share (34.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Symptom NOS involving neurological and muscular skeletal SOCs (#1411 of 2,481 by report volume); death-coded 34.0%. PlainBreed reaction plate · death-coded share stamp 34.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →