Reaction profile

The FDA adverse-event record for symptom nos involving neurological and muscular skeletal socs

93 FDA adverse-event reports reference symptom nos involving neurological and muscular skeletal socs (VeDDRA 1822). See the species, breeds, and drugs most associated with it below.

93
reports citing this reaction
34.4%
death-coded share
Dog
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
93
Total Reports
32
Deaths
34.4%
Death Rate

Species Most Affected

Dog 65
Cat 12
Turkey 10
Chicken 2
Horse 2
Cattle 1
Rabbit 1

Breeds Most Affected

Turkey (unknown) 9
Domestic Shorthair 9
Retriever - Labrador 5
Boxer (German Boxer) 4
Crossbred Canine/dog 3
Dachshund (unspecified) 3
Poodle - Toy 3
Terrier - Yorkshire 3
Terrier - Bull - American Pit 3
Retriever - Golden 3

Associated Drugs

Monensin Sodium 11
Sarolaner 11
Pyrantel Pamoate;Sarolaner 9
Bedinvetmab 8
Milbemycin Oxime + Spinosad 7
Moxidectin 7
Gabapentin 7
Supplement 5
Trilostane 5
Selamectin 3
Carprofen 3
Rabies Vaccine 3
Vaccines (Unknown) 2
Diphenhydramine 2
Buprenorphine 2
Tramadol 2
Milbemycin Oxime 2
Ivermectin + Pyrantel As Pamoate Salt 2
Oclacitinib Maleate 2
Melarsomine Dihydrochloride 2

Symptom NOS involving neurological and muscular skeletal SOCs Reaction Insights

93 reports name Symptom NOS involving neurological and muscular skeletal SOCs; 32 recorded a death outcome (34.4% of reported events, not a population-level mortality rate). VeDDRA code: 1822.

By species: Dog (65 reports), Cat (12 reports), Turkey (10 reports). By breed: Turkey (unknown) (9), Domestic Shorthair (9), Retriever - Labrador (5).

Most co-reported drugs: Monensin Sodium (11 reports), Sarolaner (11 reports), Pyrantel Pamoate;Sarolaner (9 reports), Bedinvetmab (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.