Reaction profile

The FDA adverse-event record for discus prolapse

108 FDA adverse-event reports reference discus prolapse (VeDDRA 599). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1350 of 2,481
by report volume (all reactions)
108
reports citing this reaction
23.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Discus prolapse has 108 reports now versus 108 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Discus prolapse changes

FDA AER · VeDDRA plate

Code 599 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 108 reports
  • DEATH-HOT 23.1%
  • MID-PACK #1350/2481
  • PHOTO-FINISH Acid-base disorder
  • SPECIES-DOG Dog · 107
  • DRUG-LEAD Milbemycin Oxime… · 30
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acid-base disorder (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Discus prolapse

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acid-base disorder · near108Discus prolapse · this react…108Heart pounding · near108Lick granuloma · near108Nasal cavity and sinu… · near108Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Discus prolapse

What the FDA AER plate says about Discus prolapse

Signature read: death-coded share at 23.1% is the most distinctive outcome stamp on Discus prolapse. Report volume sits in the middle third of the reaction corpus. 25 of 108 reports were death-coded (23.1% of named reports, not a population mortality rate). Nearest volume peer: Acid-base disorder (±0 reports). Lead species Dog (107). Lead co-reported drug Milbemycin Oxime + Spinosad (30).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 107
Cat 1

Breeds Most Affected

Retriever - Labrador 12
Dachshund (unspecified) 9
Crossbred Canine/dog 8
Schnauzer (unspecified) 5
Dachshund - Miniature 5
Bulldog - French 5
Shepherd Dog - German 4
Terrier - Yorkshire 4
Spaniel - Cocker American 3
Shih Tzu 3

Associated Drugs

Milbemycin Oxime + Spinosad 30
Spinosad 15
Trilostane 15
Carprofen 14
Gabapentin 9
Bedinvetmab 8
Cyclosporine 4
Meloxicam 4
Oclacitinib Maleate 4
Methocarbamol 3
Selamectin 3
Prednisone 3
Milbemycin Oxime 3
Afoxolaner 3
Milbemycin Oxime + Praziquantel 3
Fluralaner 13.64% 12-Week Chew 3
Nitenpyram 2
Deracoxib 2
Alprazolam 2
Vaccines (Unknown) 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Discus prolapse, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (108 here).

Similar death-coded share

Nearest other reactions by death-coded share (23.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Discus prolapse (#1350 of 2,481 by report volume); death-coded 23.1%. PlainBreed reaction plate · death-coded share stamp 23.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →