Reaction profile

The FDA adverse-event record for pr-lung(s), lesion(s)

537 FDA adverse-event reports reference pr-lung(s), lesion(s) (VeDDRA 99631). See the species, breeds, and drugs most associated with it below.

537
reports citing this reaction
97.8%
death-coded share
Dog
most-affected species
Tildipirosin
most-associated drug
Verify with FDA CVM →
537
Total Reports
525
Deaths
97.8%
Death Rate

Species Most Affected

Dog 200
Cattle 198
Cat 114
Horse 9
Pig 4
Sheep 4
Guinea Pig 1
Buffalo 1
Chicken 1
Other 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 60
Domestic (unspecified) 51
Crossbred Bovine/Cattle 42
Domestic Shorthair 37
Cattle (other) 36
Retriever - Labrador 29
Cattle (unknown) 25
Crossbred Canine/dog 23
Aberdeen Angus 18
Dachshund (unspecified) 10

Associated Drugs

Tildipirosin 39
Moxidectin 34
Tulathromycin 31
Florfenicol, Flunixin 31
Carprofen 27
Cefovecin Sodium 26
Cefovecin 25
Robenacoxib 24
Ceftiofur Crystalline Free Acid 21
Maropitant Citrate 19
Fluralaner Chew Tablets 19
Dexmedetomidine Hydrochloride 16
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 16
Afoxolaner 15
Spinosad 14
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 14
Oclacitinib Maleate 14
Maropitant 13
Enrofloxacin 12
Milbemycin Oxime + Spinosad 12

PR-LUNG(S), LESION(S) Reaction Insights

537 reports name PR-LUNG(S), LESION(S); 525 recorded a death outcome (97.8% of reported events, not a population-level mortality rate). VeDDRA code: 99631.

By species: Dog (200 reports), Cattle (198 reports), Cat (114 reports). By breed: Holstein-Friesian also known as Holstein (60), Domestic (unspecified) (51), Crossbred Bovine/Cattle (42).

Most co-reported drugs: Tildipirosin (39 reports), Moxidectin (34 reports), Tulathromycin (31 reports), Florfenicol, Flunixin (31 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.