Reaction profile

The FDA adverse-event record for pr-lung(s), lesion(s)

539 FDA reports name pr-lung(s), lesion(s), a high-volume reaction in the CVM extract (VeDDRA 99631). Plate stamps and neighbourhood peers follow.

#615 of 2,481
by report volume (all reactions)
539
reports citing this reaction
97.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-LUNG(S), LESION(S) has 539 reports now versus 538 in that prior snapshot: 1 more (0.2%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-LUNG(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99631 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 539 reports
  • DEATH-HOT 97.8%
  • UPPER-Q #615/2481
  • PHOTO-FINISH Prolonged capillary r…
  • SPECIES-DOG Dog · 202
  • DRUG-LEAD Tildipirosin · 39
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Prolonged capillary refill time (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around PR-LUNG, LESION

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Prolonged capillary r… · near541Urination · near541PR-LUNG(S), LESION(S) · this…539Application site blee… · near536Localised oedema (not… · near536Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-LUNG(S), LESION(S)

PR-LUNG(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-LUNG(S), LESION(S)'s 97.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume is upper-third scale: 539 named reports in the openFDA extract. Death-coded share is upper-third: 527 of 539 reports (97.8% of named reports). Nearest volume peer: Prolonged capillary refill time (±2 reports). Lead species Dog (202). Lead co-reported drug Tildipirosin (39).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 202
Cattle 198
Cat 114
Horse 9
Pig 4
Sheep 4
Guinea Pig 1
Buffalo 1
Chicken 1
Snake 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 60
Domestic (unspecified) 51
Crossbred Bovine/Cattle 42
Domestic Shorthair 37
Cattle (other) 36
Retriever - Labrador 30
Cattle (unknown) 25
Crossbred Canine/dog 24
Aberdeen Angus 18
Dachshund (unspecified) 10

Associated Drugs

Tildipirosin 39
Moxidectin 34
Tulathromycin 31
Florfenicol, Flunixin 31
Carprofen 27
Cefovecin Sodium 26
Cefovecin 25
Robenacoxib 24
Ceftiofur Crystalline Free Acid 21
Maropitant Citrate 19
Fluralaner Chew Tablets 19
Dexmedetomidine Hydrochloride 16
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 16
Afoxolaner 15
Spinosad 14
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 14
Oclacitinib Maleate 14
Maropitant 13
Enrofloxacin 12
Milbemycin Oxime + Spinosad 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-LUNG(S), LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (97.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-LUNG(S), LESION(S) (#615 of 2,481 by report volume); death-coded 97.8%. PlainBreed reaction plate · death-coded share stamp 97.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →