Reaction profile

The FDA adverse-event record for miosis

331 FDA adverse-event reports reference miosis (VeDDRA 680). See the species, breeds, and drugs most associated with it below.

331
reports citing this reaction
25.1%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
331
Total Reports
83
Deaths
25.1%
Death Rate

Species Most Affected

Dog 214
Cat 116
Horse 1

Breeds Most Affected

Domestic Shorthair 65
Crossbred Canine/dog 28
Domestic (unspecified) 16
Retriever - Labrador 15
Shepherd Dog - Australian 11
Chihuahua 10
Dachshund (unspecified) 9
Shepherd Dog - German 7
Domestic Longhair 7
Siberian Husky 6

Associated Drugs

Maropitant Citrate 30
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 30
Milbemycin Oxime + Spinosad 26
Moxidectin 16
Buprenorphine 15
Melarsomine Dihydrochloride 14
Florfenicol, Terbinafine, Betamethasone Acetate 14
Bedinvetmab 14
Spinosad 13
Prednisone 13
Melarsomine Dihydrochloride Injection 13
Carprofen 12
Enrofloxacin 11
Cefovecin Sodium 10
Dexamethasone 10
Midazolam 10
Propofol 9
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 9
Selamectin 8
Ivermectin 8

Miosis Reaction Insights

331 reports name Miosis; 83 recorded a death outcome (25.1% of reported events, not a population-level mortality rate). VeDDRA code: 680.

By species: Dog (214 reports), Cat (116 reports), Horse (1 reports). By breed: Domestic Shorthair (65), Crossbred Canine/dog (28), Domestic (unspecified) (16).

Most co-reported drugs: Maropitant Citrate (30 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (30 reports), Milbemycin Oxime + Spinosad (26 reports), Moxidectin (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.