Reaction profile

The FDA adverse-event record for oral cavity disorder nos

478 FDA reports name oral cavity disorder nos, a high-volume reaction in the CVM extract (VeDDRA 2229). Plate stamps and neighbourhood peers follow.

#659 of 2,481
by report volume (all reactions)
478
reports citing this reaction
16.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Oral cavity disorder NOS has 478 reports now versus 469 in that prior snapshot: 9 more (1.9%).

Report change
+9
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Oral cavity disorder NOS changes

FDA AER · VeDDRA plate

Code 2229 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 478 reports
  • DEATH-ELEV 16.3%
  • MID-PACK #659/2481
  • PHOTO-FINISH Abdominal effusion
  • SPECIES-DOG Dog · 325
  • DRUG-LEAD Oclacitinib Malea… · 60
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal effusion (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Oral cavity disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypocalcaemia · near481Respiratory signs · near481Proprioception abnorm… · near480Abdominal effusion · near478Oral cavity disorder… · this…478Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Oral cavity disorder NOS

What the FDA AER plate says about Oral cavity disorder NOS

Signature read: 78 death-coded reports is a heavy tail count for Oral cavity disorder NOS in the CVM extract. Report volume is upper-third scale: 478 named reports in the openFDA extract. 78 of 478 reports were death-coded (16.3% of named reports, not a population mortality rate). Nearest volume peer: Abdominal effusion (±0 reports). Lead species Dog (325). Lead co-reported drug Oclacitinib Maleate (60).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 325
Cat 100
Horse 26
Human 18
Chicken 2
Cattle 2
Rabbit 2
Pig 2
Donkey 1

Breeds Most Affected

Domestic Shorthair 49
Retriever - Labrador 28
Unknown 19
Chihuahua 18
Retriever - Golden 18
Crossbred Canine/dog 13
Shih Tzu 13
Boxer (German Boxer) 12
Terrier - Yorkshire 11
Shepherd Dog - German 11

Associated Drugs

Oclacitinib Maleate 60
Milbemycin Oxime + Spinosad 50
Afoxolaner 28
Maropitant Citrate 24
Carprofen 23
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 21
Ivermectin + Pyrantel As Pamoate Salt 20
Bedinvetmab 18
Cefovecin 16
Moxidectin 15
Anti-Il31 Mab Mcs Lot #1283563 15
Gabapentin 14
Spinosad 14
Milbemycin Oxime + Praziquantel 14
Selamectin 13
Robenacoxib 13
Cyclosporine 13
Prednisone 13
Buprenorphine 13
Trilostane 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Oral cavity disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (478 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Oral cavity disorder NOS (#659 of 2,481 by report volume); death-coded 16.3%. PlainBreed reaction plate · death-coded report count stamp 78 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →