Reaction profile

The FDA adverse-event record for urine abnormalities nos

1,930 FDA adverse-event reports reference urine abnormalities nos (VeDDRA 1959). See the species, breeds, and drugs most associated with it below.

1,930
reports citing this reaction
16.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
1,930
Total Reports
316
Deaths
16.4%
Death Rate

Species Most Affected

Dog 1,613
Cat 296
Horse 13
Human 4
Cattle 1
Sheep 1
Parrot 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 218
Domestic Shorthair 197
Crossbred Canine/dog 81
Retriever - Golden 79
Shih Tzu 62
Shepherd Dog - German 62
Boxer (German Boxer) 53
Chihuahua 48
Terrier - Yorkshire 45
Shepherd Dog - Australian 43

Associated Drugs

Carprofen 299
Milbemycin Oxime + Spinosad 225
Oclacitinib Maleate 207
Maropitant Citrate 173
Trilostane 166
Bedinvetmab 126
Gabapentin 91
Afoxolaner 69
Cefovecin 68
Spinosad 66
Bexagliflozin 65
Famotidine 60
Enrofloxacin 59
Meloxicam 58
Buprenorphine 57
Milbemycin Oxime + Praziquantel 57
Prednisone 55
Tramadol 55
Moxidectin 55
Fluralaner Chew Tablets 53

Urine abnormalities NOS Reaction Insights

1,930 reports name Urine abnormalities NOS; 316 recorded a death outcome (16.4% of reported events, not a population-level mortality rate). VeDDRA code: 1959.

By species: Dog (1,613 reports), Cat (296 reports), Horse (13 reports). By breed: Retriever - Labrador (218), Domestic Shorthair (197), Crossbred Canine/dog (81).

Most co-reported drugs: Carprofen (299 reports), Milbemycin Oxime + Spinosad (225 reports), Oclacitinib Maleate (207 reports), Maropitant Citrate (173 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.