Reaction profile

The FDA adverse-event record for cirrhosis

Name: Cirrhosis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

19 FDA adverse-event reports reference cirrhosis (VeDDRA 487). See the species, breeds, and drugs most associated with it below.

19
reports citing this reaction: 36.8%
death-coded share: Dog
most-affected species: Carprofen
most-associated drug

Compiled by PlainBreed Editorial, Pet Health Editorial Team

Verify with FDA CVM →

Total Reports

Deaths

36.8%

Death Rate

Species Most Affected

Dog 18

Cat 1

Breeds Most Affected

Retriever - Labrador 10

Collie (unspecified) 1

Chihuahua 1

Spaniel - Cocker American 1

Havanese 1

Saint Bernard Dog 1

Terrier - Jack Russell 1

Dog (unknown) 1

Domestic Shorthair 1

Bulldog - American 1

Associated Drugs

Carprofen 9

Milbemycin Oxime + Spinosad 3

Amoxicillin 3

Oclacitinib Maleate 3

Maropitant Citrate 2

Fluralaner Chew Tablets 2

Deracoxib 2

Gabapentin 2

Balanced Electrolyte Solution 2

Sadenosylmethionine And Silybin 2

Polysulfated Glycosaminoglycan 1

(Activated Whole Raw Pancreas) 1

Levothyroxine 1

Dexmedetomidine Hydrochloride 1

Canine B Burgdorferi *2 Alu Kb 1

Vaccine 1

Acepromazine 1

Butorphanol Tartrate 1

Cefazolin 1

Isoflurane 1

Cirrhosis Reaction Insights

19 reports name Cirrhosis; 7 recorded a death outcome (36.8% of reported events, not a population-level mortality rate). VeDDRA code: 487.

By species: Dog (18 reports), Cat (1 reports). By breed: Retriever - Labrador (10), Collie (unspecified) (1), Chihuahua (1).

Most co-reported drugs: Carprofen (9 reports), Milbemycin Oxime + Spinosad (3 reports), Amoxicillin (3 reports), Oclacitinib Maleate (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.