Reaction profile

The FDA adverse-event record for luxation/subluxation

114 FDA adverse-event reports reference luxation/subluxation (VeDDRA 2912). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1332 of 2,481
by report volume (all reactions)
114
reports citing this reaction
15.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Luxation/subluxation has 114 reports now versus 98 in that prior snapshot: 16 more (16.3%).

Report change
+16
Death-coded reports
+5
Death-coded share
+2.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Luxation/subluxation changes

FDA AER · VeDDRA plate

Code 2912 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 114 reports
  • DEATH-ELEV 15.8%
  • MID-PACK #1332/2481
  • PHOTO-FINISH Abdominal cramp
  • SPECIES-DOG Dog · 100
  • DRUG-LEAD Bedinvetmab · 62
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal cramp (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Luxation/subluxation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abdominal cramp · near114Application site oede… · near114Greasy skin · near114Hard stool · near114Luxation/subluxation · this …114Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Luxation/subluxation

What the FDA AER plate says about Luxation/subluxation

Signature read: report volume at 114 (#1332 of 2,481) is the standout scale stamp on Luxation/subluxation. Report volume sits in the middle third of the reaction corpus. 18 of 114 reports were death-coded (15.8% of named reports, not a population mortality rate). Nearest volume peer: Abdominal cramp (±0 reports). Lead species Dog (100). Lead co-reported drug Bedinvetmab (62).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 100
Cat 14

Breeds Most Affected

Dog (unknown) 10
Retriever - Labrador 10
Chihuahua 8
Crossbred Canine/dog 8
Domestic Shorthair 7
Shih Tzu 5
Retriever - Golden 4
Terrier (unspecified) 4
Boxer (German Boxer) 3
Shepherd (unspecified) 3

Associated Drugs

Bedinvetmab 62
Carprofen 29
Gabapentin 29
Frunevetmab 13
Prednisone 10
Diphenhydramine 10
Oclacitinib Maleate 8
Polysulfated Glycosaminoglycan 8
Galliprant 7
Grapiprant 7
Famotidine 6
Lotilaner 6
Fluralaner 13.64% 12-Week Chew 5
Sarolaner 5
Prednisolone 5
Milbemycin Oxime + Praziquantel 4
Maropitant Citrate 4
Clindamycin 4
Afoxolaner 4
Tigilanol Tiglate 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Luxation/subluxation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (114 here).

Similar death-coded share

Nearest other reactions by death-coded share (15.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Luxation/subluxation (#1332 of 2,481 by report volume); death-coded 15.8%. PlainBreed reaction plate · report volume stamp 114 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →