Reaction profile

The FDA adverse-event record for luxation/subluxation

81 FDA adverse-event reports reference luxation/subluxation (VeDDRA 2912). See the species, breeds, and drugs most associated with it below.

81
reports citing this reaction
14.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
81
Total Reports
12
Deaths
14.8%
Death Rate

Species Most Affected

Dog 73
Cat 8

Breeds Most Affected

Dog (unknown) 9
Retriever - Labrador 7
Crossbred Canine/dog 4
Shih Tzu 4
Terrier (unspecified) 4
Chihuahua 3
Boxer (German Boxer) 3
Shepherd (unspecified) 3
Great Pyrenees 3
Domestic Shorthair 3

Associated Drugs

Bedinvetmab 43
Gabapentin 22
Carprofen 20
Diphenhydramine 8
Prednisone 7
Frunevetmab 7
Galliprant 7
Oclacitinib Maleate 6
Famotidine 6
Sarolaner 5
Fluralaner 13.64% 12-Week Chew 4
Grapiprant 4
Clindamycin 4
Afoxolaner 4
Tigilanol Tiglate 4
Prednisolone 4
Anti-Il31 Mab Mcs Lot #1283563 3
Pyrantel Pamoate;Sarolaner 3
Lotilaner 3
Cyclosporine (Ophthalmic) 3

Luxation/subluxation Reaction Insights

81 reports name Luxation/subluxation; 12 recorded a death outcome (14.8% of reported events, not a population-level mortality rate). VeDDRA code: 2912.

By species: Dog (73 reports), Cat (8 reports). By breed: Dog (unknown) (9), Retriever - Labrador (7), Crossbred Canine/dog (4).

Most co-reported drugs: Bedinvetmab (43 reports), Gabapentin (22 reports), Carprofen (20 reports), Diphenhydramine (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.