Reaction profile

The FDA adverse-event record for iga animal morbidity greater than expected

Name: IGA Animal morbidity greater than expected - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

53 FDA reports name iga animal morbidity greater than expected, a lower-volume reaction in the CVM extract (VeDDRA 93103). Plate stamps and neighbourhood peers follow.

#1707 of 2,481
by report volume (all reactions): 53
reports citing this reaction: 88.7%
death-coded share: Chicken
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. IGA Animal morbidity greater than expected has 53 reports now versus 49 in that prior snapshot: 4 more (8.2%).

Report change: +4
Death-coded reports: +2
Death-coded share: −3.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to IGA Animal morbidity greater than expected changes

FDA AER · VeDDRA plate

Code 93103 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CHICKEN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

VOL-LOW 53 reports
DEATH-HOT 88.7%
MID-PACK #1707/2481
PHOTO-FINISH Bloody foam in mouth…
SPECIES-CHICKEN Chicken · 25
DRUG-LEAD Atlantic Salmon T… · 17
DESK-NARROW 3 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Bloody foam in mouth and nose (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around IGA Animal morbidity greater than expected

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around IGA Animal morbidity greater than expected

IGA Animal morbidity greater than expected: high death-coded share in the FDA AER plate

Signature read: IGA Animal morbidity greater than expected's 88.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 53 named reports in the openFDA extract. Death-coded share is upper-third: 47 of 53 reports (88.7% of named reports). Nearest volume peer: Bloody foam in mouth and nose (±0 reports). Lead species Chicken (25). Lead co-reported drug Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) (17).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Chicken 25

Fish 17

Pig 10

Chinchilla 1

Breeds Most Affected

Unknown 26

Atlantic Salmon (Salmo salar) 17

Pig (other) 10

Associated Drugs

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) 17

Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. 16

Deletion Of Exon 7 Of Cd163 Gene In Domestic Pigs 10

Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal 9

Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. Further, These Animals Are Back-Up Genetic Flock Not Used For Sebelipase Alfa Production. 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for IGA Animal morbidity greater than expected, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (53 here).

Bloody foam in mouth and nose 53 Decreased skin turgor 53 Easily startled 53 Footpad disorder NOS 53

Similar death-coded share

Nearest other reactions by death-coded share (88.7% here), distinct from the volume row.

Foam in the trachea 88.3% Lack of efficacy (bacteria) - Mannheimia haemolytica 89.5% Ruminal bloat 87.8% Cardiorespiratory arrest 87.7%

What to do with this reaction

Compare IGA Animal morbidity greater than expected's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for IGA Animal morbidity greater than expected (#1707 of 2,481 by report volume); death-coded 88.7%. PlainBreed reaction plate · death-coded share stamp 88.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →