Reaction profile

The FDA adverse-event record for gum bruising

17 FDA adverse-event reports reference gum bruising (VeDDRA 1887). See the species, breeds, and drugs most associated with it below.

17
reports citing this reaction
29.4%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
17
Total Reports
5
Deaths
29.4%
Death Rate

Species Most Affected

Dog 16
Cat 1

Breeds Most Affected

Deutsche Dogge, Great Dane 2
Boxer (German Boxer) 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Poodle - Miniature 1
Catahoula Leopard Dog 1
Shih Tzu 1
Dog (unknown) 1
Shar Pei 1
Brittany 1
Crossbred Canine/dog 1

Associated Drugs

Moxidectin 3
Spinosad 2
Milbemycin Oxime + Spinosad 2
Cefovecin 2
Bedinvetmab 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Imidacloprid + Moxidectin 1
Enrofloxacin 1
Unknown Vaccines 1
Unspecified 1
Glucosamine, Perna Canaliculus, Creatine Monohydrate & Msm 1
Firocoxib 227 Mg Chewable 1
Cefpodoxime Proxetil 1
Furosemide 1
Prednisone 1
Metoclopramide 1
Lotilaner 1
Afoxolaner 1
Ivermectin + Pyrantel 1
Meloxicam 1

Gum bruising Reaction Insights

17 reports name Gum bruising; 5 recorded a death outcome (29.4% of reported events, not a population-level mortality rate). VeDDRA code: 1887.

By species: Dog (16 reports), Cat (1 reports). By breed: Deutsche Dogge, Great Dane (2), Boxer (German Boxer) (2), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (1).

Most co-reported drugs: Moxidectin (3 reports), Spinosad (2 reports), Milbemycin Oxime + Spinosad (2 reports), Cefovecin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.