Gum bruising

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VeDDRA Code: 1887

17 adverse event reports referencing this reaction

17
Total Reports
5
Deaths
2940.0%
Death Rate

Species Most Affected

Dog 16
Cat 1

Breeds Most Affected

Deutsche Dogge, Great Dane 2
Boxer (German Boxer) 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Poodle - Miniature 1
Catahoula Leopard Dog 1
Shih Tzu 1
Dog (unknown) 1
Shar Pei 1
Brittany 1
Crossbred Canine/dog 1

Associated Drugs

Moxidectin 3
Spinosad 2
Milbemycin Oxime + Spinosad 2
Cefovecin 2
Bedinvetmab 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Imidacloprid + Moxidectin 1
Enrofloxacin 1
Unknown Vaccines 1
Unspecified 1
Glucosamine, Perna Canaliculus, Creatine Monohydrate & Msm 1
Firocoxib 227 Mg Chewable 1
Cefpodoxime Proxetil 1
Furosemide 1
Prednisone 1
Metoclopramide 1
Lotilaner 1
Afoxolaner 1
Ivermectin + Pyrantel 1
Meloxicam 1

Data Summary

Metric Value
Total reports referencing reaction 17
Reports with fatal outcome 5
Case-fatality rate (reported events) 2940.0%
Species observed 2
Breeds observed 15
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1887.

Gum bruising Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 17 adverse event reports that reference Gum bruising as a reaction term, including 5 reports with a death outcome — a 2940.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1887, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Gum bruising appears most frequently in reports for Dog (16 reports), Cat (1 reports) — with Dog dominating at 16 entries. Within those species, the breeds most often named alongside this reaction are Deutsche Dogge, Great Dane (2), Boxer (German Boxer) (2), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Gum bruising are Moxidectin (3 reports), Spinosad (2 reports), Milbemycin Oxime + Spinosad (2 reports), Cefovecin (2 reports), with Moxidectin appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial