Hypoalbuminaemia

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VeDDRA Code: 1883

3,312 adverse event reports referencing this reaction

3,312
Total Reports
1,078
Deaths
3250.0%
Death Rate

Species Most Affected

Dog 2,971
Cat 304
Horse 27
Cattle 6
Other Canids 1
Pig 1
Ferret 1
Mouse 1

Breeds Most Affected

Retriever - Labrador 467
Crossbred Canine/dog 190
Domestic Shorthair 170
Retriever - Golden 160
Terrier - Yorkshire 112
Shepherd Dog - German 95
Chihuahua 88
Pug 74
Boxer (German Boxer) 72
Shih Tzu 71

Associated Drugs

Carprofen 572
Maropitant Citrate 443
Oclacitinib Maleate 381
Deracoxib 199
Milbemycin Oxime + Spinosad 173
Afoxolaner 162
Meloxicam 156
Gabapentin 149
Moxidectin 146
Metronidazole 144
Famotidine 142
Prednisone 135
Cefovecin 131
Bedinvetmab 130
Enrofloxacin 126
Grapiprant 123
Fluralaner Chew Tablets 122
Trilostane 103
Tramadol 102
Buprenorphine 101

Data Summary

Metric Value
Total reports referencing reaction 3,312
Reports with fatal outcome 1,078
Case-fatality rate (reported events) 3250.0%
Species observed 8
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1883.

Hypoalbuminaemia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 3,312 adverse event reports that reference Hypoalbuminaemia as a reaction term, including 1,078 reports with a death outcome — a 3250.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1883, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hypoalbuminaemia appears most frequently in reports for Dog (2,971 reports), Cat (304 reports), Horse (27 reports) — with Dog dominating at 2,971 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (467), Crossbred Canine/dog (190), Domestic Shorthair (170). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hypoalbuminaemia are Carprofen (572 reports), Maropitant Citrate (443 reports), Oclacitinib Maleate (381 reports), Deracoxib (199 reports), with Carprofen appearing alongside this reaction in 572 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial