Reaction profile

The FDA adverse-event record for hypoalbuminaemia

3,488 FDA reports name hypoalbuminaemia, a high-volume reaction in the CVM extract (VeDDRA 1883). Plate stamps and neighbourhood peers follow.

#132 of 2,481
by report volume (all reactions)
3,488
reports citing this reaction
32.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypoalbuminaemia has 3,488 reports now versus 3,399 in that prior snapshot: 89 more (2.6%).

Report change
+89
Death-coded reports
+18
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypoalbuminaemia changes

FDA AER · VeDDRA plate

Code 1883 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 3,488 reports
  • DEATH-HOT 32.1%
  • TOP-DECILE #132/2481
  • PHOTO-FINISH Tubes, Leaking
  • SPECIES-DOG Dog · 3,116
  • DRUG-LEAD Carprofen · 595
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tubes, Leaking (±21 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hypoalbuminaemia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Tubes, Leaking · near3509Hypoalbuminaemia · this reac…3488Convulsion · near3461Dilated pupils · near3461Lateral recumbency · near3455Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypoalbuminaemia

Hypoalbuminaemia: high death-coded share in the FDA AER plate

Signature read: 1,118 death-coded reports is a heavy tail count for Hypoalbuminaemia in the CVM extract. Report volume is upper-third scale: 3,488 named reports in the openFDA extract. Death-coded share is upper-third: 1,118 of 3,488 reports (32.1% of named reports). Nearest volume peer: Tubes, Leaking (±21 reports). Lead species Dog (3,116). Lead co-reported drug Carprofen (595).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 3,116
Cat 327
Horse 35
Cattle 6
Other Canids 1
Ferret 1
Pig 1
Mouse 1

Breeds Most Affected

Retriever - Labrador 489
Crossbred Canine/dog 198
Domestic Shorthair 182
Retriever - Golden 165
Terrier - Yorkshire 113
Shepherd Dog - German 106
Chihuahua 95
Pug 75
Boxer (German Boxer) 74
Shih Tzu 72

Associated Drugs

Carprofen 595
Maropitant Citrate 495
Oclacitinib Maleate 405
Deracoxib 200
Gabapentin 175
Milbemycin Oxime + Spinosad 174
Afoxolaner 167
Meloxicam 163
Metronidazole 162
Moxidectin 159
Bedinvetmab 151
Famotidine 147
Prednisone 144
Cefovecin 138
Enrofloxacin 135
Grapiprant 126
Fluralaner Chew Tablets 122
Buprenorphine 119
Trilostane 109
Cyclosporine 105

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hypoalbuminaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (3,488 here).

Similar death-coded share

Nearest other reactions by death-coded share (32.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypoalbuminaemia (#132 of 2,481 by report volume); death-coded 32.1%. PlainBreed reaction plate · death-coded report count stamp 1,118 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →