Haemoconcentration

Verify with FDA CVM →

VeDDRA Code: 2272

278 adverse event reports referencing this reaction

278
Total Reports
57
Deaths
2050.0%
Death Rate

Species Most Affected

Dog 253
Cat 24
Ferret 1

Breeds Most Affected

Retriever - Labrador 33
Domestic Shorthair 14
Crossbred Canine/dog 14
Terrier - Yorkshire 13
Chihuahua 13
Boxer (German Boxer) 9
Shepherd Dog - German 9
Terrier - Bull - American Pit 9
Terrier (unspecified) 8
Bulldog - French 7

Associated Drugs

Maropitant Citrate 47
Carprofen 36
Moxidectin 34
Ivermectin + Pyrantel As Pamoate Salt 21
Milbemycin Oxime + Spinosad 20
Afoxolaner 19
Famotidine 18
Oclacitinib Maleate 17
Fluralaner Chew Tablets 13
Pyrantel Pamoate;Sarolaner 13
Buprenorphine 11
Diphenhydramine Hcl 11
Meloxicam 10
Isoflurane 10
Dexamethasone 10
Metronidazole 10
Propofol 10
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 10
Deracoxib 9
Sarolaner 9

Data Summary

Metric Value
Total reports referencing reaction 278
Reports with fatal outcome 57
Case-fatality rate (reported events) 2050.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2272.

Haemoconcentration Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 278 adverse event reports that reference Haemoconcentration as a reaction term, including 57 reports with a death outcome — a 2050.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2272, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Haemoconcentration appears most frequently in reports for Dog (253 reports), Cat (24 reports), Ferret (1 reports) — with Dog dominating at 253 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (33), Domestic Shorthair (14), Crossbred Canine/dog (14). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Haemoconcentration are Maropitant Citrate (47 reports), Carprofen (36 reports), Moxidectin (34 reports), Ivermectin + Pyrantel As Pamoate Salt (21 reports), with Maropitant Citrate appearing alongside this reaction in 47 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial