Injection site scab

Verify with FDA CVM →

VeDDRA Code: 85

383 adverse event reports referencing this reaction

383
Total Reports
6
Deaths
160.0%
Death Rate

Species Most Affected

Dog 267
Cat 106
Cattle 5
Horse 2
Rat 1
Sheep 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 66
Retriever - Labrador 31
Dog (unknown) 21
Retriever - Golden 11
Terrier - Bull - American Pit 11
Pit Bull 11
Shepherd Dog - German 10
Domestic Mediumhair 10
Boxer (German Boxer) 10
Crossbred Canine/dog 8

Associated Drugs

Carprofen 74
Tigilanol Tiglate 73
Gabapentin 69
Diphenhydramine 57
Famotidine 57
Prednisone 52
Maropitant Citrate 48
Cefovecin 43
Frunevetmab 34
Buprenorphine 30
Butorphanol 30
Butorphanol Tartrate 28
Meloxicam 24
Enrofloxacin 23
Dexmedetomidine Hydrochloride 23
Dexmedetomidine 22
Atipamezole Hydrochloride 22
Propofol 20
Moxidectin 20
Bedinvetmab 20

Data Summary

Metric Value
Total reports referencing reaction 383
Reports with fatal outcome 6
Case-fatality rate (reported events) 160.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 85.

Injection site scab Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 383 adverse event reports that reference Injection site scab as a reaction term, including 6 reports with a death outcome — a 160.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 85, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Injection site scab appears most frequently in reports for Dog (267 reports), Cat (106 reports), Cattle (5 reports) — with Dog dominating at 267 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (66), Retriever - Labrador (31), Dog (unknown) (21). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Injection site scab are Carprofen (74 reports), Tigilanol Tiglate (73 reports), Gabapentin (69 reports), Diphenhydramine (57 reports), with Carprofen appearing alongside this reaction in 74 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial