Reaction profile

The FDA adverse-event record for injection site scab

406 FDA reports name injection site scab, a high-volume reaction in the CVM extract (VeDDRA 85). Plate stamps and neighbourhood peers follow.

#718 of 2,481
by report volume (all reactions)
406
reports citing this reaction
1.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site scab has 406 reports now versus 395 in that prior snapshot: 11 more (2.8%).

Report change
+11
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site scab changes

FDA AER · VeDDRA plate

Code 85 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 406 reports
  • DEATH-LOW 1.5%
  • MID-PACK #718/2481
  • PHOTO-FINISH Product defect NOS
  • SPECIES-DOG Dog · 284
  • DRUG-LEAD Tigilanol Tiglate · 85
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Product defect NOS (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Injection site scab

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Injection site erythe… · near407Injection site scab · this r…406Product defect NOS · near406Loss of vision · near405Oral ulceration · near405Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site scab

Injection site scab: low death-coded share in the FDA AER plate

Signature read: Injection site scab's 1.5% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 406 named reports in the openFDA extract. Death-coded share is lower-third: 6 of 406 reports (1.5% of named reports). Nearest volume peer: Product defect NOS (±0 reports). Lead species Dog (284). Lead co-reported drug Tigilanol Tiglate (85).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 284
Cat 112
Cattle 5
Horse 2
Rat 1
Rabbit 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 71
Retriever - Labrador 33
Dog (unknown) 21
Retriever - Golden 13
Terrier - Bull - American Pit 12
Pit Bull 12
Domestic Mediumhair 11
Boxer (German Boxer) 11
Shepherd Dog - German 10
Crossbred Canine/dog 9

Associated Drugs

Tigilanol Tiglate 85
Carprofen 76
Gabapentin 74
Famotidine 66
Diphenhydramine 64
Prednisone 60
Maropitant Citrate 51
Cefovecin 45
Frunevetmab 36
Butorphanol 34
Buprenorphine 30
Butorphanol Tartrate 29
Dexmedetomidine Hydrochloride 25
Enrofloxacin 24
Meloxicam 24
Dexmedetomidine 24
Atipamezole Hydrochloride 22
Bedinvetmab 21
Propofol 20
Moxidectin 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site scab, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (406 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site scab (#718 of 2,481 by report volume); death-coded 1.5%. PlainBreed reaction plate · death-coded share stamp 1.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →