Reaction profile

The FDA adverse-event record for lack of efficacy (bacteria) - bordetella

Name: Lack of efficacy (bacteria) - Bordetella - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

38 FDA reports name lack of efficacy (bacteria) - bordetella, a lower-volume reaction in the CVM extract (VeDDRA 3013). Plate stamps and neighbourhood peers follow.

#1878 of 2,481
by report volume (all reactions): 38
reports citing this reaction: 7.9%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (bacteria) - Bordetella has 38 reports now versus 37 in that prior snapshot: 1 more (2.7%).

Report change: +1
Death-coded reports: +1
Death-coded share: +2.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (bacteria) - Bordetella changes

FDA AER · VeDDRA plate

Code 3013 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 38 reports
DEATH-PAR 7.9%
LOWER-Q #1878/2481
PHOTO-FINISH Clenched jaw
SPECIES-DOG Dog · 37
DRUG-LEAD Oral Bordetella C… · 10
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - Bordetella

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Lack of efficacy (bacteria) - Bordetella

Lack of efficacy (bacteria) - Bordetella: low death-coded share in the FDA AER plate

Signature read: 3 death-coded reports is a thin tail count for Lack of efficacy (bacteria) - Bordetella in the CVM extract. Report volume is lower-third scale: 38 named reports in the openFDA extract. Death-coded share is lower-third: 3 of 38 reports (7.9% of named reports). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (37). Lead co-reported drug Oral Bordetella Canine - 1081.01 (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oral Bordetella Canine - 1081.01 appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 37

Cat 1

Breeds Most Affected

Retriever - Golden 5

Shepherd Dog - German 4

Retriever - Labrador 3

Boxer (German Boxer) 2

Terrier - Boston 2

Terrier (unspecified) 2

Pit Bull 2

Crossbred Canine/dog 2

Pug 2

Setter - English 2

Associated Drugs

Oral Bordetella Canine - 1081.01 10

Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 10

Lotilaner 8

Milbemycin Oxime + Praziquantel 8

Ivermectin + Pyrantel As Pamoate Salt 7

Afoxolaner 5

Rabies Vaccine 5

Bordetella Bronchiseptica, Boehringer Ingelheim Strain 5

Doxycycline 4

Enrofloxacin 4

Maropitant Citrate 3

Fluralaner 13.64% 12-Week Chew 2

Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2

Canine Influenza Vaccine 2

Benazepril 2

Fenbendazole 2

Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 2

Estriol Tablets 2

Bordetella Bronchiseptica B-C2 2

Oclacitinib Maleate 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (bacteria) - Bordetella (#1878 of 2,481 by report volume); death-coded 7.9%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →