Reaction profile

The FDA adverse-event record for peripheral vascular disorder

19 FDA adverse-event reports reference peripheral vascular disorder (VeDDRA 1690). See the species, breeds, and drugs most associated with it below.

19
reports citing this reaction
21.1%
death-coded share
Dog
most-affected species
Noinformationsupplied
most-associated drug
Verify with FDA CVM →
19
Total Reports
4
Deaths
21.1%
Death Rate

Species Most Affected

Dog 12
Horse 3
Pig 1
Cattle 1
Human 1
Cat 1

Breeds Most Affected

Dog (unknown) 3
Terrier - Jack Russell 2
Thoroughbred 2
Schnauzer - Miniature 1
Collie - Border 1
Pug 1
Spitz - German Pomeranian 1
Pig (unknown) 1
Charolais 1
Terrier - Bull - Staffordshire 1

Associated Drugs

Noinformationsupplied 11
Dexmedetomidine Hydrochloride 5
Trilostane 3
Ampicillin Sodium & Sulbactam Sodium 2
Milbemycin Oxime + Spinosad 1
Nitenpyram 1
Afoxolaner 1
Device: Cardiovascular 1
Eprinomectin 5 Mg/Ml Pour-On Solution 1
Moxidectin 1
Rabies Virus, 1
Hetastarch 1
Maropitant Citrate 1
Anti-Il31 Mab Mcs Lot #1283563 1
Famotidine 1
Ondansetron Hcl 1
Enrofloxacin 1
Diphenhydramine Hcl 1
Ceftiofur Sodium 1
Ceftiofur Crystalline Free Acid 1

Peripheral vascular disorder Reaction Insights

19 reports name Peripheral vascular disorder; 4 recorded a death outcome (21.1% of reported events, not a population-level mortality rate). VeDDRA code: 1690.

By species: Dog (12 reports), Horse (3 reports), Pig (1 reports). By breed: Dog (unknown) (3), Terrier - Jack Russell (2), Thoroughbred (2).

Most co-reported drugs: Noinformationsupplied (11 reports), Dexmedetomidine Hydrochloride (5 reports), Trilostane (3 reports), Ampicillin Sodium & Sulbactam Sodium (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.