Peripheral vascular disorder

Verify with FDA CVM →

VeDDRA Code: 1690

19 adverse event reports referencing this reaction

19
Total Reports
4
Deaths
2110.0%
Death Rate

Species Most Affected

Dog 12
Horse 3
Pig 1
Cattle 1
Human 1
Cat 1

Breeds Most Affected

Dog (unknown) 3
Terrier - Jack Russell 2
Thoroughbred 2
Schnauzer - Miniature 1
Collie - Border 1
Pug 1
Spitz - German Pomeranian 1
Pig (unknown) 1
Charolais 1
Terrier - Bull - Staffordshire 1

Associated Drugs

Noinformationsupplied 11
Dexmedetomidine Hydrochloride 5
Trilostane 3
Ampicillin Sodium & Sulbactam Sodium 2
Milbemycin Oxime + Spinosad 1
Nitenpyram 1
Afoxolaner 1
Device: Cardiovascular 1
Eprinomectin 5 Mg/Ml Pour-On Solution 1
Moxidectin 1
Rabies Virus, 1
Hetastarch 1
Maropitant Citrate 1
Anti-Il31 Mab Mcs Lot #1283563 1
Famotidine 1
Ondansetron Hcl 1
Enrofloxacin 1
Diphenhydramine Hcl 1
Ceftiofur Sodium 1
Ceftiofur Crystalline Free Acid 1

Data Summary

Metric Value
Total reports referencing reaction 19
Reports with fatal outcome 4
Case-fatality rate (reported events) 2110.0%
Species observed 6
Breeds observed 15
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1690.

Peripheral vascular disorder Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 19 adverse event reports that reference Peripheral vascular disorder as a reaction term, including 4 reports with a death outcome — a 2110.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1690, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Peripheral vascular disorder appears most frequently in reports for Dog (12 reports), Horse (3 reports), Pig (1 reports) — with Dog dominating at 12 entries. Within those species, the breeds most often named alongside this reaction are Dog (unknown) (3), Terrier - Jack Russell (2), Thoroughbred (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Peripheral vascular disorder are Noinformationsupplied (11 reports), Dexmedetomidine Hydrochloride (5 reports), Trilostane (3 reports), Ampicillin Sodium & Sulbactam Sodium (2 reports), with Noinformationsupplied appearing alongside this reaction in 11 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial