Reaction profile

The FDA adverse-event record for generalised allergic reaction nos

133 FDA adverse-event reports reference generalised allergic reaction nos (VeDDRA 1115). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1248 of 2,481
by report volume (all reactions)
133
reports citing this reaction
7.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Generalised allergic reaction NOS has 133 reports now versus 133 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Generalised allergic reaction NOS changes

FDA AER · VeDDRA plate

Code 1115 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 133 reports
  • DEATH-PAR 7.5%
  • MID-PACK #1248/2481
  • PHOTO-FINISH Gastric dilation
  • SPECIES-DOG Dog · 108
  • DRUG-LEAD Moxidectin · 16
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Gastric dilation (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Generalised allergic reaction NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Gastric dilation · near133Generalised allergic… · this…133Pitting oedema · near133Application site muco… · near132Cyanotic mucous membr… · near132Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Generalised allergic reaction NOS

Generalised allergic reaction NOS: low death-coded share in the FDA AER plate

Signature read: Generalised allergic reaction NOS's 7.5% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 10 of 133 reports (7.5% of named reports). Nearest volume peer: Gastric dilation (±0 reports). Lead species Dog (108). Lead co-reported drug Moxidectin (16).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 108
Cattle 9
Cat 7
Human 5
Horse 4

Breeds Most Affected

Retriever - Labrador 10
Chihuahua 7
Dog (unknown) 7
Unknown 6
Shih Tzu 5
Dachshund (unspecified) 5
Crossbred Canine/dog 4
Bulldog - French 4
Pit Bull 4
Holstein-Friesian also known as Holstein 3

Associated Drugs

Moxidectin 16
Desoxycorticosterone Pivalate 15
Lufenuron + Milbemycin Oxime 14
Cyclosporine A 13
Prednisone 10
Nitenpyram 9
Buprenorphine 3
Milbemycin Oxime 3
Carprofen 3
Polysulfated Glycosaminoglycan 3
Deracoxib 3
Grapiprant 3
Rabies Virus, 3
Trimeprazine/Prednisolone 2
Fipronil, Cyphenothrin 2
Dexamethasone 2
Doxycycline 2
Triamcinolone Acetonide 2
Cefovecin 2
Imidacloprid 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Generalised allergic reaction NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (7.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Generalised allergic reaction NOS (#1248 of 2,481 by report volume); death-coded 7.5%. PlainBreed reaction plate · death-coded share stamp 7.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →