Reaction profile

The FDA adverse-event record for lack of efficacy (mite)

42 FDA reports name lack of efficacy (mite), a lower-volume reaction in the CVM extract (VeDDRA 2652). Plate stamps and neighbourhood peers follow.

#1830 of 2,481
by report volume (all reactions)
42
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (mite) has 42 reports now versus 42 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (mite) changes

FDA AER · VeDDRA plate

Code 2652 VOL-TRACE

VOL-TRACE · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 42 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1830/2481
  • PHOTO-FINISH Allergy to food
  • SPECIES-DOG Dog · 21
  • DRUG-LEAD Selamectin · 12
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Allergy to food (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Allergy to food · near42Asystole · near42Cholecystitis · near42Cutaneous emphysema · near42Lack of efficacy (mit… · thi…42Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (mite)

Lack of efficacy (mite): low death-coded share in the FDA AER plate

Signature read: Lack of efficacy (mite)'s 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 42 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 42 reports (0.0% of named reports). Nearest volume peer: Allergy to food (±0 reports). Lead species Dog (21). Lead co-reported drug Selamectin (12).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 21
Cat 10
Cattle 9
Guinea Pig 1
Pig 1

Breeds Most Affected

Dog (unknown) 7
Domestic Shorthair 5
Cattle (unknown) 4
Cat (other) 3
Holstein-Friesian also known as Holstein 2
Shepherd Dog - Australian 2
Mixed (Cattle) 2
Retriever - Labrador 2
Terrier (unspecified) 1
Boxer (German Boxer) 1

Associated Drugs

Selamectin 12
Fluralaner Chew Tablets 5
Eprinomectin 5 Mg/Ml Pour-On Solution 4
Afoxolaner 4
Doramectin 3
Sarolaner 3
Eprinomectin 3
Fluralaner 2
Milbemycin Oxime + Praziquantel 1
Oclacitinib Maleate 1
Afoxolaner 136 Mg Chewable Tablets 1
Fluralaner Spot-On Solution 1
Milbemycin Oxime + Spinosad 1
Lotilaner 1
Cephalexin 1
Cefovecin 1
Methylprednisolone Acetate 1
Selamectin;Sarolaner 1
Antibiotic 1
Fluralaner 13.64% Chew Tablets 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (mite) (#1830 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →