Reaction profile

The FDA adverse-event record for injection site gaseous gangrene

20 FDA reports name injection site gaseous gangrene, a lower-volume reaction in the CVM extract (VeDDRA 2094). Plate stamps and neighbourhood peers follow.

#2166 of 2,481
by report volume (all reactions)
20
reports citing this reaction
85.0%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site gaseous gangrene has 20 reports now versus 20 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site gaseous gangrene changes

FDA AER · VeDDRA plate

Code 2094 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 20 reports
  • DEATH-HOT 85.0%
  • LOWER-Q #2166/2481
  • PHOTO-FINISH Agalactia
  • SPECIES-CATTLE Cattle · 16
  • DRUG-LEAD Dinoprost Trometh… · 16
  • DESK-WIDE 8 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Agalactia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Injection site gaseous gangrene

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Agalactia · near20Application site pigm… · near20Application site skin… · near20Cirrhosis · near20Injection site gaseou… · thi…20Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site gaseous gangrene

Injection site gaseous gangrene: high death-coded share in the FDA AER plate

Signature read: Injection site gaseous gangrene's 85.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 20 named reports in the openFDA extract. Death-coded share is upper-third: 17 of 20 reports (85.0% of named reports). Nearest volume peer: Agalactia (±0 reports). Lead species Cattle (16). Lead co-reported drug Dinoprost Tromethamine (16).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 16
Cat 2
Horse 1
Dog 1

Breeds Most Affected

Cattle (other) 9
Holstein-Friesian also known as Holstein 5
Horse (unknown) 1
Ragdoll 1
Cattle (unspecified) 1
Aberdeen Angus 1
Pinscher - Miniature 1
Maine Coon 1

Associated Drugs

Dinoprost Tromethamine 16
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 4
Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Haemolyticum, Strain Ir 2
Ivermectin 1
Cefovecin Sodium 1
Ceftiofur Hydrochloride 1
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 1
Gnrh 1
Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 1
Tigilanol Tiglate 1
Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296 1
Unknown Clostridial Vaccine 1
Buprenorphine 1
Feline Leukemia Virus, Ah927/1161E Strain 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site gaseous gangrene (#2166 of 2,481 by report volume); death-coded 85.0%. PlainBreed reaction plate · death-coded share stamp 85.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →