Pancreatitis

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VeDDRA Code: 1891

2,708 adverse event reports referencing this reaction

2,708
Total Reports
576
Deaths
2130.0%
Death Rate

Species Most Affected

Dog 2,404
Cat 301
Other Birds 1
Cockatiel 1
Human 1

Breeds Most Affected

Terrier - Yorkshire 185
Crossbred Canine/dog 167
Retriever - Labrador 162
Domestic Shorthair 161
Chihuahua 118
Dog (unknown) 93
Boxer (German Boxer) 75
Maltese 73
Schnauzer - Miniature 69
Dachshund (unspecified) 67

Associated Drugs

Milbemycin Oxime + Spinosad 371
Trilostane 296
Maropitant Citrate 225
Carprofen 206
Oclacitinib Maleate 173
Fluralaner Chew Tablets 155
Afoxolaner 130
Spinosad 122
Insulin Injectable Vial 103
Ivermectin + Pyrantel As Pamoate Salt 100
Moxidectin 86
Grapiprant 82
Famotidine 75
Metronidazole 71
Prednisone 63
Meloxicam 59
Cefovecin 59
Buprenorphine 57
Deracoxib 54
Imidacloprid + Moxidectin 54

Data Summary

Metric Value
Total reports referencing reaction 2,708
Reports with fatal outcome 576
Case-fatality rate (reported events) 2130.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1891.

Pancreatitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,708 adverse event reports that reference Pancreatitis as a reaction term, including 576 reports with a death outcome — a 2130.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1891, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pancreatitis appears most frequently in reports for Dog (2,404 reports), Cat (301 reports), Other Birds (1 reports) — with Dog dominating at 2,404 entries. Within those species, the breeds most often named alongside this reaction are Terrier - Yorkshire (185), Crossbred Canine/dog (167), Retriever - Labrador (162). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pancreatitis are Milbemycin Oxime + Spinosad (371 reports), Trilostane (296 reports), Maropitant Citrate (225 reports), Carprofen (206 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 371 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial