Reaction profile

The FDA adverse-event record for pancreatitis

2,707 FDA reports name pancreatitis, a high-volume reaction in the CVM extract (VeDDRA 1891). Plate stamps and neighbourhood peers follow.

#173 of 2,481
by report volume (all reactions)
2,707
reports citing this reaction
21.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pancreatitis has 2,707 reports now versus 2,707 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pancreatitis changes

FDA AER · VeDDRA plate

Code 1891 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,707 reports
  • DEATH-HOT 21.3%
  • TOP-DECILE #173/2481
  • PHOTO-FINISH Elevated serum alkali…
  • SPECIES-DOG Dog · 2,403
  • DRUG-LEAD Milbemycin Oxime… · 371
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated serum alkaline phosphatase (ALP) (±6 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Pancreatitis

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Urticaria · near2718Lymphopenia · near2716Pancreatitis · this reaction2707Elevated serum alkali… · near2701INEFFECTIVE, HEARTWOR… · near2694Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pancreatitis

What the FDA AER plate says about Pancreatitis

Signature read: 576 death-coded reports is a heavy tail count for Pancreatitis in the CVM extract. Report volume is upper-third scale: 2,707 named reports in the openFDA extract. 576 of 2,707 reports were death-coded (21.3% of named reports, not a population mortality rate). Nearest volume peer: Elevated serum alkaline phosphatase (ALP) (±6 reports). Lead species Dog (2,403). Lead co-reported drug Milbemycin Oxime + Spinosad (371).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,403
Cat 301
Other Birds 1
Cockatiel 1
Human 1

Breeds Most Affected

Terrier - Yorkshire 185
Crossbred Canine/dog 167
Retriever - Labrador 162
Domestic Shorthair 161
Chihuahua 118
Dog (unknown) 93
Boxer (German Boxer) 75
Maltese 73
Schnauzer - Miniature 69
Dachshund (unspecified) 67

Associated Drugs

Milbemycin Oxime + Spinosad 371
Trilostane 296
Maropitant Citrate 225
Carprofen 206
Oclacitinib Maleate 173
Fluralaner Chew Tablets 155
Afoxolaner 130
Spinosad 122
Insulin Injectable Vial 103
Ivermectin + Pyrantel As Pamoate Salt 100
Moxidectin 86
Grapiprant 82
Famotidine 75
Metronidazole 71
Prednisone 63
Meloxicam 59
Cefovecin 59
Buprenorphine 57
Deracoxib 54
Imidacloprid + Moxidectin 54

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pancreatitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (21.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pancreatitis (#173 of 2,481 by report volume); death-coded 21.3%. PlainBreed reaction plate · death-coded report count stamp 576 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →