Reaction profile

The FDA adverse-event record for increased respiratory rate

1,534 FDA reports name increased respiratory rate, a high-volume reaction in the CVM extract (VeDDRA 856). Plate stamps and neighbourhood peers follow.

#279 of 2,481
by report volume (all reactions)
1,534
reports citing this reaction
25.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased respiratory rate has 1,534 reports now versus 1,490 in that prior snapshot: 44 more (3.0%).

Report change
+44
Death-coded reports
+6
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased respiratory rate changes

FDA AER · VeDDRA plate

Code 856 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,534 reports
  • DEATH-HOT 25.4%
  • UPPER-Q #279/2481
  • PHOTO-FINISH Arthritis
  • SPECIES-DOG Dog · 1,001
  • DRUG-LEAD Maropitant Citrate · 113
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Arthritis (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Increased respiratory rate

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Arthritis · near1535Increased respiratory… · thi…1534Contamination, Foreig… · near1531Staring · near1531Thrombocytosis · near1529Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased respiratory rate

Increased respiratory rate: high death-coded share in the FDA AER plate

Signature read: 390 death-coded reports is a heavy tail count for Increased respiratory rate in the CVM extract. Report volume is upper-third scale: 1,534 named reports in the openFDA extract. Death-coded share is upper-third: 390 of 1,534 reports (25.4% of named reports). Nearest volume peer: Arthritis (±1 reports). Lead species Dog (1,001). Lead co-reported drug Maropitant Citrate (113).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,001
Cat 420
Horse 76
Cattle 24
Rabbit 5
Donkey 2
Pig 2
Sheep 1
Goat 1
Human 1

Breeds Most Affected

Domestic Shorthair 261
Retriever - Labrador 88
Crossbred Canine/dog 74
Shepherd Dog - German 47
Domestic Longhair 44
Retriever - Golden 42
Shih Tzu 38
Terrier - Yorkshire 37
Chihuahua 37
Domestic Mediumhair 31

Associated Drugs

Maropitant Citrate 113
Milbemycin Oxime + Spinosad 105
Moxidectin 98
Gabapentin 96
Pimobendan 79
Buprenorphine 79
Carprofen 75
Nitenpyram 64
Cefovecin 59
Prednisone 58
Melarsomine Dihydrochloride 58
Bedinvetmab 56
Furosemide 52
Selamectin 49
Afoxolaner 44
Isoflurane 43
Enrofloxacin 42
Diphenhydramine 42
Spinosad 39
Tramadol 39

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased respiratory rate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,534 here).

Similar death-coded share

Nearest other reactions by death-coded share (25.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased respiratory rate (#279 of 2,481 by report volume); death-coded 25.4%. PlainBreed reaction plate · death-coded report count stamp 390 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →