Unkempt hair coat

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VeDDRA Code: 2757

78 adverse event reports referencing this reaction

78
Total Reports
17
Deaths
2180.0%
Death Rate

Species Most Affected

Cat 59
Dog 15
Cattle 2
Pig 1
Horse 1

Breeds Most Affected

Domestic Shorthair 33
Domestic Longhair 6
Domestic Mediumhair 6
Maine Coon 3
Cat (other) 2
Cat (unknown) 2
Shepherd Dog - German 2
Collie - Border 2
Holstein-Friesian also known as Holstein 2
Spitz - German Pomeranian 2

Associated Drugs

Frunevetmab 18
Bexagliflozin 12
Velagliflozin Proline Monohydrate 12
Maropitant Citrate 5
Bedinvetmab 5
Ondansetron 4
Prednisolone 4
Cefovecin 4
Selamectin;Sarolaner 3
Trilostane 3
Prednisone 3
Protamine Zinc Recombinant Human Insulin 3
Buprenorphine 3
Fluid Therapy 3
Potassium Chloride 3
Ampicillin Sodium/Sulbactam Sodium 3
Senvelgo Velagliflozin Oral Solution 3
Diphenhydramine 3
Famotidine 3
Verdinexor 2

Data Summary

Metric Value
Total reports referencing reaction 78
Reports with fatal outcome 17
Case-fatality rate (reported events) 2180.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2757.

Unkempt hair coat Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 78 adverse event reports that reference Unkempt hair coat as a reaction term, including 17 reports with a death outcome — a 2180.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2757, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Unkempt hair coat appears most frequently in reports for Cat (59 reports), Dog (15 reports), Cattle (2 reports) — with Cat dominating at 59 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (33), Domestic Longhair (6), Domestic Mediumhair (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Unkempt hair coat are Frunevetmab (18 reports), Bexagliflozin (12 reports), Velagliflozin Proline Monohydrate (12 reports), Maropitant Citrate (5 reports), with Frunevetmab appearing alongside this reaction in 18 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial