Reaction profile

The FDA adverse-event record for glaucoma

203 FDA adverse-event reports reference glaucoma (VeDDRA 417). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1027 of 2,481
by report volume (all reactions)
203
reports citing this reaction
16.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Glaucoma has 203 reports now versus 198 in that prior snapshot: 5 more (2.5%).

Report change
+5
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Glaucoma changes

FDA AER · VeDDRA plate

Code 417 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 203 reports
  • DEATH-ELEV 16.3%
  • MID-PACK #1027/2481
  • PHOTO-FINISH Anal irritation
  • SPECIES-DOG Dog · 181
  • DRUG-LEAD Milbemycin Oxime… · 28
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anal irritation (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Glaucoma

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348INEFFECTIVE, PRODUCTI… · near204Anal irritation · near203Glaucoma · this reaction203Increased sexual inte… · near202Loss of voluntary mov… · near202Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Glaucoma

What the FDA AER plate says about Glaucoma

Signature read: 33 death-coded reports is the most distinctive absolute-outcome stamp on Glaucoma. Report volume sits in the middle third of the reaction corpus. 33 of 203 reports were death-coded (16.3% of named reports, not a population mortality rate). Nearest volume peer: Anal irritation (±0 reports). Lead species Dog (181). Lead co-reported drug Milbemycin Oxime + Spinosad (28).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 181
Cat 21
Rabbit 1

Breeds Most Affected

Retriever - Labrador 18
Shih Tzu 14
Spaniel - Cocker American 10
Crossbred Canine/dog 10
Domestic Shorthair 10
Terrier - Boston 7
Pug 6
Maltese 6
Siamese 6
Lhasa Apso 5

Associated Drugs

Milbemycin Oxime + Spinosad 28
Trilostane 21
Carprofen 15
Oclacitinib Maleate 14
Spinosad 11
Insulin Injectable Vial 10
Bedinvetmab 10
Prednisone 7
Grapiprant 7
Frunevetmab 7
Recombinant Human Insulin 6
Moxidectin 6
Ivermectin + Pyrantel As Pamoate Salt 6
Afoxolaner 6
Milbemycin Oxime + Praziquantel 6
Insulin 5
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 5
Anti-Il31 Mab Mcs Lot #1283563 5
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 5
Cefovecin Sodium 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Glaucoma, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (16.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Glaucoma (#1027 of 2,481 by report volume); death-coded 16.3%. PlainBreed reaction plate · death-coded report count stamp 33 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →