Reaction profile

The FDA adverse-event record for glaucoma

193 FDA adverse-event reports reference glaucoma (VeDDRA 417). See the species, breeds, and drugs most associated with it below.

193
reports citing this reaction
16.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
193
Total Reports
32
Deaths
16.6%
Death Rate

Species Most Affected

Dog 172
Cat 20
Rabbit 1

Breeds Most Affected

Retriever - Labrador 16
Shih Tzu 13
Spaniel - Cocker American 10
Crossbred Canine/dog 10
Domestic Shorthair 9
Pug 6
Maltese 6
Terrier - Boston 6
Siamese 6
Dog (unknown) 5

Associated Drugs

Milbemycin Oxime + Spinosad 28
Trilostane 19
Oclacitinib Maleate 13
Carprofen 12
Spinosad 11
Insulin Injectable Vial 10
Prednisone 7
Frunevetmab 7
Bedinvetmab 7
Recombinant Human Insulin 6
Grapiprant 6
Afoxolaner 6
Milbemycin Oxime + Praziquantel 6
Insulin 5
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 5
Moxidectin 5
Ivermectin + Pyrantel As Pamoate Salt 5
Anti-Il31 Mab Mcs Lot #1283563 5
Firocoxib 4
Cefpodoxime Proxetil 4

Glaucoma Reaction Insights

193 reports name Glaucoma; 32 recorded a death outcome (16.6% of reported events, not a population-level mortality rate). VeDDRA code: 417.

By species: Dog (172 reports), Cat (20 reports), Rabbit (1 reports). By breed: Retriever - Labrador (16), Shih Tzu (13), Spaniel - Cocker American (10).

Most co-reported drugs: Milbemycin Oxime + Spinosad (28 reports), Trilostane (19 reports), Oclacitinib Maleate (13 reports), Carprofen (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.