Reaction profile

The FDA adverse-event record for pyelonephritis

137 FDA adverse-event reports reference pyelonephritis (VeDDRA 716). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1234 of 2,481
by report volume (all reactions)
137
reports citing this reaction
37.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pyelonephritis has 137 reports now versus 133 in that prior snapshot: 4 more (3.0%).

Report change
+4
Death-coded reports
+1
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pyelonephritis changes

FDA AER · VeDDRA plate

Code 716 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 137 reports
  • DEATH-HOT 37.2%
  • MID-PACK #1234/2481
  • PHOTO-FINISH Drowsiness - neurolog…
  • SPECIES-DOG Dog · 87
  • DRUG-LEAD Maropitant Citrate · 21
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Drowsiness - neurological disorder (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Pyelonephritis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Drowsiness - neurolog… · near137Megaoesophagus · near137Pyelonephritis · this reacti…137White blood cell diso… · near137Tracheal and laryngea… · near136Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pyelonephritis

Pyelonephritis: high death-coded share in the FDA AER plate

Signature read: Pyelonephritis's 37.2% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 51 of 137 reports (37.2% of named reports). Nearest volume peer: Drowsiness - neurological disorder (±0 reports). Lead species Dog (87). Lead co-reported drug Maropitant Citrate (21).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 87
Cat 47
Horse 2
Cattle 1

Breeds Most Affected

Domestic Shorthair 29
Retriever - Labrador 8
Crossbred Canine/dog 6
Domestic Longhair 5
Beagle 4
Shih Tzu 4
Terrier (unspecified) 3
Terrier - Boston 3
Maltese 3
Cat (unknown) 3

Associated Drugs

Maropitant Citrate 21
Trilostane 18
Carprofen 13
Milbemycin Oxime + Spinosad 11
Oclacitinib Maleate 11
Gabapentin 11
Bedinvetmab 11
Enrofloxacin 10
Buprenorphine 9
Cefovecin 8
Furosemide 7
Cefovecin Sodium 6
Bexagliflozin 6
Frunevetmab 6
Doxycycline 5
Afoxolaner 5
Meloxicam 5
Pimobendan 5
Cyclosporine 5
Prednisone 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pyelonephritis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (37.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pyelonephritis (#1234 of 2,481 by report volume); death-coded 37.2%. PlainBreed reaction plate · death-coded share stamp 37.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →