Reaction profile

The FDA adverse-event record for lying down

908 FDA reports name lying down, a high-volume reaction in the CVM extract (VeDDRA 2743). Plate stamps and neighbourhood peers follow.

#423 of 2,481
by report volume (all reactions)
908
reports citing this reaction
18.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lying down has 908 reports now versus 870 in that prior snapshot: 38 more (4.4%).

Report change
+38
Death-coded reports
+7
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lying down changes

FDA AER · VeDDRA plate

Code 2743 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 908 reports
  • DEATH-ELEV 18.8%
  • UPPER-Q #423/2481
  • PHOTO-FINISH Application site burn
  • SPECIES-DOG Dog · 602
  • DRUG-LEAD Bedinvetmab · 87
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site burn (±3 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Lying down

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Arrhythmia · near918Application site burn · near911Lying down · this reaction908Star-gazing · near904Application site reac… · near897Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lying down

What the FDA AER plate says about Lying down

Signature read: 171 death-coded reports is a heavy tail count for Lying down in the CVM extract. Report volume is upper-third scale: 908 named reports in the openFDA extract. 171 of 908 reports were death-coded (18.8% of named reports, not a population mortality rate). Nearest volume peer: Application site burn (±3 reports). Lead species Dog (602). Lead co-reported drug Bedinvetmab (87).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 602
Cat 163
Horse 97
Cattle 34
Turkey 3
Goat 3
Pig 2
Other Equids 1
Camel 1
Rat 1

Breeds Most Affected

Domestic Shorthair 89
Retriever - Labrador 66
Crossbred Canine/dog 42
Retriever - Golden 35
Shepherd Dog - German 33
Domestic Longhair 32
Chihuahua 31
Quarter Horse 29
Shepherd Dog - Australian 21
Siberian Husky 19

Associated Drugs

Bedinvetmab 87
Pyrantel Pamoate;Sarolaner 65
Fluralaner 13.64% 12-Week Chew 63
Gabapentin 59
Afoxolaner 57
Maropitant Citrate 52
Milbemycin Oxime + Praziquantel 50
Moxidectin 48
Carprofen 42
Lotilaner 30
Buprenorphine 30
Ceftiofur Crystalline Free Acid 28
Prednisone 27
Milbemycin Oxime + Spinosad 26
Frunevetmab 23
Nitenpyram 21
Fluralaner Spot-On Solution 20
Trilostane 20
Diphenhydramine 20
Sarolaner 19

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lying down, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (908 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lying down (#423 of 2,481 by report volume); death-coded 18.8%. PlainBreed reaction plate · death-coded report count stamp 171 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →