Reaction profile

The FDA adverse-event record for lying down

794 FDA adverse-event reports reference lying down (VeDDRA 2743). See the species, breeds, and drugs most associated with it below.

794
reports citing this reaction
18.0%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
794
Total Reports
143
Deaths
18.0%
Death Rate

Species Most Affected

Dog 529
Cat 136
Horse 87
Cattle 32
Turkey 3
Goat 3
Pig 2
Other Equids 1
Camel 1

Breeds Most Affected

Domestic Shorthair 75
Retriever - Labrador 60
Crossbred Canine/dog 40
Quarter Horse 29
Retriever - Golden 28
Chihuahua 27
Shepherd Dog - German 25
Domestic Longhair 25
Shepherd Dog - Australian 19
Siberian Husky 18

Associated Drugs

Bedinvetmab 75
Fluralaner 13.64% 12-Week Chew 60
Pyrantel Pamoate;Sarolaner 59
Afoxolaner 50
Gabapentin 48
Moxidectin 43
Milbemycin Oxime + Praziquantel 42
Carprofen 37
Maropitant Citrate 36
Milbemycin Oxime + Spinosad 26
Buprenorphine 26
Lotilaner 25
Ceftiofur Crystalline Free Acid 24
Prednisone 20
Sarolaner 19
Nitenpyram 18
Fluralaner Spot-On Solution 17
Ivermectin + Pyrantel As Pamoate Salt 17
Detomidine Hydrochloride 16
Trilostane 16

Lying down Reaction Insights

794 reports name Lying down; 143 recorded a death outcome (18.0% of reported events, not a population-level mortality rate). VeDDRA code: 2743.

By species: Dog (529 reports), Cat (136 reports), Horse (87 reports). By breed: Domestic Shorthair (75), Retriever - Labrador (60), Crossbred Canine/dog (40).

Most co-reported drugs: Bedinvetmab (75 reports), Fluralaner 13.64% 12-Week Chew (60 reports), Pyrantel Pamoate;Sarolaner (59 reports), Afoxolaner (50 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.