Reaction profile

The FDA adverse-event record for stumbling gait

2,134 FDA adverse-event reports reference stumbling gait (VeDDRA 657). See the species, breeds, and drugs most associated with it below.

2,134
reports citing this reaction
14.9%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
2,134
Total Reports
318
Deaths
14.9%
Death Rate

Species Most Affected

Dog 1,762
Cat 297
Horse 35
Cattle 28
Goat 4
Other 2
Rabbit 2
Rat 1
Turkey 1
Human 1

Breeds Most Affected

Retriever - Labrador 198
Domestic Shorthair 164
Crossbred Canine/dog 143
Shepherd Dog - German 95
Chihuahua 72
Terrier - Yorkshire 64
Retriever - Golden 63
Shih Tzu 59
Boxer (German Boxer) 57
Dog (unknown) 51

Associated Drugs

Milbemycin Oxime + Spinosad 266
Afoxolaner 151
Bedinvetmab 150
Carprofen 141
Spinosad 107
Fluralaner 13.64% 12-Week Chew 97
Sarolaner 92
Pyrantel Pamoate;Sarolaner 89
Fluralaner Chew Tablets 85
Trilostane 80
Ivermectin + Pyrantel As Pamoate Salt 75
Maropitant Citrate 70
Gabapentin 63
Moxidectin 55
Milbemycin Oxime + Praziquantel 55
Ivermectin 53
Selamectin 49
Oclacitinib Maleate 46
Prednisone 40
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 40

Stumbling gait Reaction Insights

2,134 reports name Stumbling gait; 318 recorded a death outcome (14.9% of reported events, not a population-level mortality rate). VeDDRA code: 657.

By species: Dog (1,762 reports), Cat (297 reports), Horse (35 reports). By breed: Retriever - Labrador (198), Domestic Shorthair (164), Crossbred Canine/dog (143).

Most co-reported drugs: Milbemycin Oxime + Spinosad (266 reports), Afoxolaner (151 reports), Bedinvetmab (150 reports), Carprofen (141 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.