Reaction profile

The FDA adverse-event record for stumbling gait

2,252 FDA reports name stumbling gait, a high-volume reaction in the CVM extract (VeDDRA 657). Plate stamps and neighbourhood peers follow.

#206 of 2,481
by report volume (all reactions)
2,252
reports citing this reaction
14.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Stumbling gait has 2,252 reports now versus 2,196 in that prior snapshot: 56 more (2.6%).

Report change
+56
Death-coded reports
+4
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Stumbling gait changes

FDA AER · VeDDRA plate

Code 657 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,252 reports
  • DEATH-ELEV 14.6%
  • TOP-DECILE #206/2481
  • PHOTO-FINISH Low platelet count
  • SPECIES-DOG Dog · 1,838
  • DRUG-LEAD Milbemycin Oxime… · 267
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Low platelet count (±5 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Stumbling gait

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Confusion · near2259Stumbling gait · this reacti…2252Low platelet count · near2247Caps, Abnormal · near2242Renal failure · near2240Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Stumbling gait

What the FDA AER plate says about Stumbling gait

Signature read: 329 death-coded reports is a heavy tail count for Stumbling gait in the CVM extract. Report volume is upper-third scale: 2,252 named reports in the openFDA extract. 329 of 2,252 reports were death-coded (14.6% of named reports, not a population mortality rate). Nearest volume peer: Low platelet count (±5 reports). Lead species Dog (1,838). Lead co-reported drug Milbemycin Oxime + Spinosad (267).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,838
Cat 332
Horse 41
Cattle 29
Goat 4
Other 2
Rabbit 2
Rat 1
Turkey 1
Human 1

Breeds Most Affected

Retriever - Labrador 210
Domestic Shorthair 186
Crossbred Canine/dog 144
Shepherd Dog - German 97
Chihuahua 77
Terrier - Yorkshire 66
Retriever - Golden 66
Boxer (German Boxer) 63
Shih Tzu 60
Dog (unknown) 51

Associated Drugs

Milbemycin Oxime + Spinosad 267
Bedinvetmab 165
Afoxolaner 155
Carprofen 148
Spinosad 107
Fluralaner 13.64% 12-Week Chew 102
Sarolaner 96
Pyrantel Pamoate;Sarolaner 92
Fluralaner Chew Tablets 85
Maropitant Citrate 84
Trilostane 83
Ivermectin + Pyrantel As Pamoate Salt 75
Gabapentin 66
Moxidectin 63
Milbemycin Oxime + Praziquantel 61
Ivermectin 56
Oclacitinib Maleate 52
Selamectin 49
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 44
Prednisone 43

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Stumbling gait, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,252 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Stumbling gait (#206 of 2,481 by report volume); death-coded 14.6%. PlainBreed reaction plate · death-coded report count stamp 329 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →