Elevated liver enzymes
VeDDRA Code: 1942
5,736 adverse event reports referencing this reaction
5,736
Total Reports
1,082
Deaths
1890.0%
Death Rate
Species Most Affected
Dog 5,316
Cat 350
Horse 44
Human 7
Cattle 7
Goat 4
Parrot 1
Guinea Pig 1
Other Canids 1
Pig 1
Breeds Most Affected
Retriever - Labrador 915
Crossbred Canine/dog 265
Dog (unknown) 229
Chihuahua 217
Shih Tzu 206
Domestic Shorthair 195
Retriever - Golden 186
Terrier - Yorkshire 134
Maltese 127
Boxer (German Boxer) 122
Associated Drugs
Carprofen 1,332
Milbemycin Oxime + Spinosad 698
Oclacitinib Maleate 515
Maropitant Citrate 435
Trilostane 352
Spinosad 262
Moxidectin 245
Grapiprant 217
Tramadol 214
Afoxolaner 188
Prednisone 185
Famotidine 178
Deracoxib 154
Metronidazole 140
Enrofloxacin 135
Sam-E, Silybin, Vitamin E, Zinc 131
Gabapentin 131
Ivermectin + Pyrantel As Pamoate Salt 128
Meloxicam 127
Milbemycin Oxime + Praziquantel 124
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.