Reaction profile

The FDA adverse-event record for hyperalbuminaemia

855 FDA adverse-event reports reference hyperalbuminaemia (VeDDRA 2154). See the species, breeds, and drugs most associated with it below.

855
reports citing this reaction
16.0%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
855
Total Reports
137
Deaths
16.0%
Death Rate

Species Most Affected

Dog 616
Cat 222
Horse 16
Cattle 1

Breeds Most Affected

Domestic Shorthair 141
Retriever - Labrador 65
Crossbred Canine/dog 46
Chihuahua 35
Shih Tzu 30
Terrier - Yorkshire 28
Retriever - Golden 22
Domestic (unspecified) 21
Maltese 20
Beagle 19

Associated Drugs

Trilostane 98
Carprofen 58
Afoxolaner 54
Maropitant Citrate 51
Bexagliflozin 50
Oclacitinib Maleate 49
Meloxicam 47
Milbemycin Oxime + Spinosad 44
Velagliflozin Proline Monohydrate 44
Ivermectin + Pyrantel As Pamoate Salt 38
Gabapentin 38
Fluralaner Chew Tablets 38
Bedinvetmab 30
Spinosad 29
Fluralaner 13.64% 12-Week Chew 27
Moxidectin 24
Prednisone 22
Pyrantel Pamoate;Sarolaner 22
Famotidine 20
Milbemycin Oxime + Praziquantel 20

Hyperalbuminaemia Reaction Insights

855 reports name Hyperalbuminaemia; 137 recorded a death outcome (16.0% of reported events, not a population-level mortality rate). VeDDRA code: 2154.

By species: Dog (616 reports), Cat (222 reports), Horse (16 reports). By breed: Domestic Shorthair (141), Retriever - Labrador (65), Crossbred Canine/dog (46).

Most co-reported drugs: Trilostane (98 reports), Carprofen (58 reports), Afoxolaner (54 reports), Maropitant Citrate (51 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.