Reaction profile

The FDA adverse-event record for hyperalbuminaemia

927 FDA reports name hyperalbuminaemia, a high-volume reaction in the CVM extract (VeDDRA 2154). Plate stamps and neighbourhood peers follow.

#417 of 2,481
by report volume (all reactions)
927
reports citing this reaction
15.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperalbuminaemia has 927 reports now versus 900 in that prior snapshot: 27 more (3.0%).

Report change
+27
Death-coded reports
+1
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperalbuminaemia changes

FDA AER · VeDDRA plate

Code 2154 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 927 reports
  • DEATH-ELEV 15.5%
  • UPPER-Q #417/2481
  • PHOTO-FINISH Lip licking
  • SPECIES-DOG Dog · 658
  • DRUG-LEAD Trilostane · 106
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lip licking (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hyperalbuminaemia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lip licking · near928Lymphadenopathy · near928Hyperalbuminaemia · this rea…927Reduced responses · near924Knuckling · near923Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperalbuminaemia

What the FDA AER plate says about Hyperalbuminaemia

Signature read: 144 death-coded reports is a heavy tail count for Hyperalbuminaemia in the CVM extract. Report volume is upper-third scale: 927 named reports in the openFDA extract. 144 of 927 reports were death-coded (15.5% of named reports, not a population mortality rate). Nearest volume peer: Lip licking (±1 reports). Lead species Dog (658). Lead co-reported drug Trilostane (106).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 658
Cat 251
Horse 17
Cattle 1

Breeds Most Affected

Domestic Shorthair 160
Retriever - Labrador 68
Crossbred Canine/dog 48
Chihuahua 38
Shih Tzu 32
Terrier - Yorkshire 30
Retriever - Golden 22
Domestic Longhair 22
Domestic (unspecified) 21
Terrier (unspecified) 21

Associated Drugs

Trilostane 106
Carprofen 59
Maropitant Citrate 58
Afoxolaner 57
Velagliflozin Proline Monohydrate 57
Oclacitinib Maleate 56
Bexagliflozin 56
Meloxicam 48
Milbemycin Oxime + Spinosad 44
Gabapentin 43
Ivermectin + Pyrantel As Pamoate Salt 41
Fluralaner Chew Tablets 38
Bedinvetmab 36
Spinosad 29
Moxidectin 28
Fluralaner 13.64% 12-Week Chew 28
Prednisone 27
Pyrantel Pamoate;Sarolaner 23
Famotidine 22
Robenacoxib 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hyperalbuminaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (927 here).

Similar death-coded share

Nearest other reactions by death-coded share (15.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperalbuminaemia (#417 of 2,481 by report volume); death-coded 15.5%. PlainBreed reaction plate · death-coded report count stamp 144 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →