Reaction profile

The FDA adverse-event record for arched back

448 FDA reports name arched back, a high-volume reaction in the CVM extract (VeDDRA 2275). Plate stamps and neighbourhood peers follow.

#686 of 2,481
by report volume (all reactions)
448
reports citing this reaction
14.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Arched back has 448 reports now versus 436 in that prior snapshot: 12 more (2.8%).

Report change
+12
Death-coded reports
+3
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Arched back changes

FDA AER · VeDDRA plate

Code 2275 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 448 reports
  • DEATH-ELEV 14.7%
  • MID-PACK #686/2481
  • PHOTO-FINISH Application site grea…
  • SPECIES-DOG Dog · 387
  • DRUG-LEAD Afoxolaner · 47
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site greasy fur (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Arched back

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Loss of bowel control · near449Application site grea… · near448Arched back · this reaction448INEFFECTIVE, EUTHANAS… · near448Gastritis · near447Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Arched back

What the FDA AER plate says about Arched back

Signature read: 66 death-coded reports is a heavy tail count for Arched back in the CVM extract. Report volume is upper-third scale: 448 named reports in the openFDA extract. 66 of 448 reports were death-coded (14.7% of named reports, not a population mortality rate). Nearest volume peer: Application site greasy fur (±0 reports). Lead species Dog (387). Lead co-reported drug Afoxolaner (47).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 387
Cat 53
Cattle 5
Horse 3

Breeds Most Affected

Crossbred Canine/dog 39
Domestic Shorthair 34
Chihuahua 25
Terrier - Yorkshire 24
Retriever - Labrador 23
Maltese 19
Retriever - Golden 19
Shih Tzu 15
Terrier - Jack Russell 10
Spitz - German Pomeranian 9

Associated Drugs

Afoxolaner 47
Milbemycin Oxime + Spinosad 43
Bedinvetmab 39
Fluralaner Chew Tablets 33
Maropitant Citrate 31
Pyrantel Pamoate;Sarolaner 31
Ivermectin + Pyrantel As Pamoate Salt 28
Carprofen 25
Gabapentin 25
Moxidectin 21
Oclacitinib Maleate 19
Buprenorphine 17
Sarolaner 16
Fluralaner 13.64% 12-Week Chew 14
Frunevetmab 14
Melarsomine Dihydrochloride Injection 12
Cefovecin 12
Lotilaner 12
Melarsomine Dihydrochloride 11
Milbemycin Oxime + Praziquantel 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Arched back, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (448 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Arched back (#686 of 2,481 by report volume); death-coded 14.7%. PlainBreed reaction plate · death-coded report count stamp 66 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →