Reaction profile

The FDA adverse-event record for arched back

424 FDA adverse-event reports reference arched back (VeDDRA 2275). See the species, breeds, and drugs most associated with it below.

424
reports citing this reaction
14.2%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
424
Total Reports
60
Deaths
14.2%
Death Rate

Species Most Affected

Dog 371
Cat 45
Cattle 5
Horse 3

Breeds Most Affected

Crossbred Canine/dog 38
Domestic Shorthair 28
Chihuahua 25
Terrier - Yorkshire 24
Retriever - Labrador 23
Retriever - Golden 18
Maltese 17
Shih Tzu 12
Terrier - Jack Russell 10
Beagle 9

Associated Drugs

Afoxolaner 44
Milbemycin Oxime + Spinosad 43
Fluralaner Chew Tablets 33
Bedinvetmab 32
Maropitant Citrate 28
Ivermectin + Pyrantel As Pamoate Salt 28
Pyrantel Pamoate;Sarolaner 28
Carprofen 25
Gabapentin 22
Moxidectin 20
Oclacitinib Maleate 18
Sarolaner 16
Buprenorphine 14
Fluralaner 13.64% 12-Week Chew 14
Melarsomine Dihydrochloride Injection 12
Frunevetmab 12
Melarsomine Dihydrochloride 11
Cefovecin 9
Lotilaner 9
Milbemycin Oxime + Praziquantel 9

Arched back Reaction Insights

424 reports name Arched back; 60 recorded a death outcome (14.2% of reported events, not a population-level mortality rate). VeDDRA code: 2275.

By species: Dog (371 reports), Cat (45 reports), Cattle (5 reports). By breed: Crossbred Canine/dog (38), Domestic Shorthair (28), Chihuahua (25).

Most co-reported drugs: Afoxolaner (44 reports), Milbemycin Oxime + Spinosad (43 reports), Fluralaner Chew Tablets (33 reports), Bedinvetmab (32 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.