Arched back

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VeDDRA Code: 2275

424 adverse event reports referencing this reaction

424
Total Reports
60
Deaths
1420.0%
Death Rate

Species Most Affected

Dog 371
Cat 45
Cattle 5
Horse 3

Breeds Most Affected

Crossbred Canine/dog 38
Domestic Shorthair 28
Chihuahua 25
Terrier - Yorkshire 24
Retriever - Labrador 23
Retriever - Golden 18
Maltese 17
Shih Tzu 12
Terrier - Jack Russell 10
Beagle 9

Associated Drugs

Afoxolaner 44
Milbemycin Oxime + Spinosad 43
Fluralaner Chew Tablets 33
Bedinvetmab 32
Maropitant Citrate 28
Ivermectin + Pyrantel As Pamoate Salt 28
Pyrantel Pamoate;Sarolaner 28
Carprofen 25
Gabapentin 22
Moxidectin 20
Oclacitinib Maleate 18
Sarolaner 16
Buprenorphine 14
Fluralaner 13.64% 12-Week Chew 14
Melarsomine Dihydrochloride Injection 12
Frunevetmab 12
Melarsomine Dihydrochloride 11
Cefovecin 9
Lotilaner 9
Milbemycin Oxime + Praziquantel 9

Data Summary

Metric Value
Total reports referencing reaction 424
Reports with fatal outcome 60
Case-fatality rate (reported events) 1420.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2275.

Arched back Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 424 adverse event reports that reference Arched back as a reaction term, including 60 reports with a death outcome — a 1420.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2275, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Arched back appears most frequently in reports for Dog (371 reports), Cat (45 reports), Cattle (5 reports) — with Dog dominating at 371 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Canine/dog (38), Domestic Shorthair (28), Chihuahua (25). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Arched back are Afoxolaner (44 reports), Milbemycin Oxime + Spinosad (43 reports), Fluralaner Chew Tablets (33 reports), Bedinvetmab (32 reports), with Afoxolaner appearing alongside this reaction in 44 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial