Reaction profile

The FDA adverse-event record for abnormal cytology

1,791 FDA adverse-event reports reference abnormal cytology (VeDDRA 2588). See the species, breeds, and drugs most associated with it below.

1,791
reports citing this reaction
12.1%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
1,791
Total Reports
217
Deaths
12.1%
Death Rate

Species Most Affected

Dog 1,488
Cat 288
Horse 14
Ferret 1

Breeds Most Affected

Retriever - Labrador 197
Domestic Shorthair 191
Retriever - Golden 100
Crossbred Canine/dog 73
Shepherd Dog - German 66
Terrier - Bull - American Pit 59
Boxer (German Boxer) 54
Chihuahua 48
Terrier - Yorkshire 35
Terrier (unspecified) 31

Associated Drugs

Oclacitinib Maleate 350
Moxidectin 201
Carprofen 185
Bedinvetmab 157
Gabapentin 145
Prednisone 129
Frunevetmab 117
Melarsomine Dihydrochloride 115
Maropitant Citrate 112
Anti-Il31 Mab Mcs Lot #1283563 110
Cefovecin 98
Fluralaner Chew Tablets 78
Enrofloxacin 64
Trilostane 62
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 57
Doxycycline 53
Afoxolaner 50
Cephalexin 48
Cefpodoxime Proxetil 47
Ivermectin + Pyrantel As Pamoate Salt 45

Abnormal cytology Reaction Insights

1,791 reports name Abnormal cytology; 217 recorded a death outcome (12.1% of reported events, not a population-level mortality rate). VeDDRA code: 2588.

By species: Dog (1,488 reports), Cat (288 reports), Horse (14 reports). By breed: Retriever - Labrador (197), Domestic Shorthair (191), Retriever - Golden (100).

Most co-reported drugs: Oclacitinib Maleate (350 reports), Moxidectin (201 reports), Carprofen (185 reports), Bedinvetmab (157 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.