Reaction profile

The FDA adverse-event record for plantigrade posture

96 FDA adverse-event reports reference plantigrade posture (VeDDRA 2632). See the species, breeds, and drugs most associated with it below.

96
reports citing this reaction
13.5%
death-coded share
Cat
most-affected species
Frunevetmab
most-associated drug
Verify with FDA CVM →
96
Total Reports
13
Deaths
13.5%
Death Rate

Species Most Affected

Cat 75
Dog 21

Breeds Most Affected

Domestic Shorthair 49
Domestic Longhair 5
Cat (other) 5
Retriever - Labrador 4
Maine Coon 3
Siamese 3
Birman (Sacred Birman) 2
Retriever - Golden 2
Cat (unknown) 2
Domestic Mediumhair 2

Associated Drugs

Frunevetmab 37
Bedinvetmab 15
Gabapentin 14
Velagliflozin Proline Monohydrate 9
Buprenorphine 8
Robenacoxib 7
Prednisolone 6
Bexagliflozin 6
Carprofen 6
Galliprant 5
Oclacitinib Maleate 5
Maropitant Citrate 4
Methimazole 4
Mirtazapine 4
Isoflurane 4
Insulin Injectable Vial 3
Enrofloxacin 3
Cefovecin 3
Protamine Zinc Recombinant Human Insulin 3
Trazodone 3

Plantigrade posture Reaction Insights

96 reports name Plantigrade posture; 13 recorded a death outcome (13.5% of reported events, not a population-level mortality rate). VeDDRA code: 2632.

By species: Cat (75 reports), Dog (21 reports). By breed: Domestic Shorthair (49), Domestic Longhair (5), Cat (other) (5).

Most co-reported drugs: Frunevetmab (37 reports), Bedinvetmab (15 reports), Gabapentin (14 reports), Velagliflozin Proline Monohydrate (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.