Reaction profile
The FDA adverse-event record for skin slough
695 FDA reports name skin slough, a high-volume reaction in the CVM extract (VeDDRA 943). Plate stamps and neighbourhood peers follow.
- #517 of 2,481
- by report volume (all reactions)
- 695
- reports citing this reaction
- 12.9%
- death-coded share
- Dog
- most-affected species
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Skin slough has 695 reports now versus 695 in that prior snapshot: 0 the same number of (0.0%).
- Report change
- +0
- Death-coded reports
- +0
- Death-coded share
- +0.0 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Skin slough changesFDA AER · VeDDRA plate
Code 943 VOL-MID
VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL
- VOL-MID 695 reports
- DEATH-ELEV 12.9%
- UPPER-Q #517/2481
- PHOTO-FINISH Expired drug administ…
- SPECIES-DOG Dog · 522
- DRUG-LEAD Tigilanol Tiglate · 133
- DESK-WIDE 20 breeds
- BOOK-FULL 8/8 fields
Nearest volume peer: Expired drug administered (±0 reports)
Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.
High-volume neighbourhood around Skin slough
Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.
What the FDA AER plate says about Skin slough
Signature read: 695 reports place Skin slough in the upper third of FDA AER volume (#517 of 2,481). Report volume is upper-third scale: 695 named reports in the openFDA extract. 90 of 695 reports were death-coded (12.9% of named reports, not a population mortality rate). Nearest volume peer: Expired drug administered (±0 reports). Lead species Dog (522). Lead co-reported drug Tigilanol Tiglate (133).
Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.
Species Most Affected
Breeds Most Affected
Associated Drugs
Nationwide reactions with similar profiles
Two openFDA-derived peer sets for Skin slough, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).
Similar report volume
Nearest other reactions by FDA report count (695 here).
Similar death-coded share
Nearest other reactions by death-coded share (12.9% here), distinct from the volume row.
What to do with this reaction
- Compare Skin slough's report profile against similar reactions nationwide. See similar reactions
- Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
- Browse the full reaction directory to compare report counts across reaction types. All reactions
A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →