Reaction profile

The FDA adverse-event record for other abnormal test result nos

21,162 FDA reports name other abnormal test result nos, a high-volume reaction in the CVM extract (VeDDRA 1221). Plate stamps and neighbourhood peers follow.

#17 of 2,481
by report volume (all reactions)
21,162
reports citing this reaction
16.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Other abnormal test result NOS has 21,162 reports now versus 20,914 in that prior snapshot: 248 more (1.2%).

Report change
+248
Death-coded reports
+35
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Other abnormal test result NOS changes

FDA AER · VeDDRA plate

Code 1221 VOL-HIGH

VOL-HIGH · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 21,162 reports
  • DEATH-ELEV 16.9%
  • TOP-DECILE #17/2481
  • PHOTO-FINISH Death by euthanasia
  • SPECIES-DOG Dog · 17,906
  • DRUG-LEAD Milbemycin Oxime… · 2,753
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Death by euthanasia (±128 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Other abnormal test result NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Digestive tract disor… · near22748Ataxia · near21626Other abnormal test r… · thi…21162Death by euthanasia · near21034Not eating · near21007Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Other abnormal test result NOS

What the FDA AER plate says about Other abnormal test result NOS

Signature read: 3,575 death-coded reports is a heavy tail count for Other abnormal test result NOS in the CVM extract. Report volume is upper-third scale: 21,162 named reports in the openFDA extract. 3,575 of 21,162 reports were death-coded (16.9% of named reports, not a population mortality rate). Nearest volume peer: Death by euthanasia (±128 reports). Lead species Dog (17,906). Lead co-reported drug Milbemycin Oxime + Spinosad (2,753).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17,906
Cat 2,610
Horse 295
Cattle 241
Human 40
Pig 24
Goat 6
Sheep 5
Chicken 5
Lion 3

Breeds Most Affected

Retriever - Labrador 2,315
Domestic Shorthair 1,696
Crossbred Canine/dog 996
Retriever - Golden 847
Shepherd Dog - German 682
Terrier - Yorkshire 577
Chihuahua 574
Shih Tzu 555
Boxer (German Boxer) 478
Beagle 429

Associated Drugs

Milbemycin Oxime + Spinosad 2,753
Milbemycin Oxime + Praziquantel 1,852
Carprofen 1,465
Oclacitinib Maleate 1,410
Afoxolaner 1,234
Maropitant Citrate 1,186
Ivermectin + Pyrantel As Pamoate Salt 1,172
Trilostane 1,165
Imidacloprid + Moxidectin 971
Lotilaner 860
Fluralaner Chew Tablets 800
Spinosad 740
Cyclosporine A 735
Deracoxib 712
Prednisone 701
Cefovecin 604
Moxidectin 550
Tramadol 508
Gabapentin 476
Enrofloxacin 445

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Other abnormal test result NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (21,162 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Other abnormal test result NOS (#17 of 2,481 by report volume); death-coded 16.9%. PlainBreed reaction plate · death-coded report count stamp 3,575 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →