Reaction profile

The FDA adverse-event record for infectious disease nos

233 FDA adverse-event reports reference infectious disease nos (VeDDRA 2597). See the species, breeds, and drugs most associated with it below.

233
reports citing this reaction
33.9%
death-coded share
Dog
most-affected species
Fluralaner 13.64% 12-Week Chew
most-associated drug
Verify with FDA CVM →
233
Total Reports
79
Deaths
33.9%
Death Rate

Species Most Affected

Dog 175
Cat 38
Cattle 8
Horse 6
Human 3
Chicken 1
Pig 1
Lynx 1

Breeds Most Affected

Crossbred Canine/dog 32
Domestic Shorthair 26
Retriever - Labrador 22
Dog (unknown) 8
Retriever - Golden 8
Pit Bull 7
Shepherd Dog - German 7
Beagle 7
Shepherd Dog - Australian 5
Collie - Border 5

Associated Drugs

Fluralaner 13.64% 12-Week Chew 44
Afoxolaner 24
Ivermectin + Pyrantel As Pamoate Salt 16
Bedinvetmab 14
Fluralaner Chew Tablets 11
Doxycycline 11
Fluralaner Spot-On Solution 11
Fenbendazol Granules 9
Gabapentin 9
Oclacitinib Maleate 7
Rabies In Hhh Adj Pfizer Kv 7
Carprofen 7
Grapiprant 7
Milbemycin Oxime + Praziquantel 6
Lotilaner 6
Pyrantel Pamoate;Sarolaner 6
Fenbendazol Suspension 5
Milbemycin/Lufenuron/Pzq Chew 5
Azithromycin 5
Milbemycin Oxime + Spinosad 4

Infectious disease NOS Reaction Insights

233 reports name Infectious disease NOS; 79 recorded a death outcome (33.9% of reported events, not a population-level mortality rate). VeDDRA code: 2597.

By species: Dog (175 reports), Cat (38 reports), Cattle (8 reports). By breed: Crossbred Canine/dog (32), Domestic Shorthair (26), Retriever - Labrador (22).

Most co-reported drugs: Fluralaner 13.64% 12-Week Chew (44 reports), Afoxolaner (24 reports), Ivermectin + Pyrantel As Pamoate Salt (16 reports), Bedinvetmab (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.